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Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source

(169)Yb has been recently used as an HDR brachytherapy source for cancer treatment. In this paper, dosimetric parameters of a new design of (169)Yb HDR brachytherapy source were determined by Monte Carlo (MC) method and film dosimetry. In this new source, the radioactive core has been encapsulated t...

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Autores principales: Safaeipour, Elham, Poorbaygi, Hosein, Jabbari, Iraj, Sheibani, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425858/
https://www.ncbi.nlm.nih.gov/pubmed/34263515
http://dx.doi.org/10.1002/acm2.13347
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author Safaeipour, Elham
Poorbaygi, Hosein
Jabbari, Iraj
Sheibani, Shahab
author_facet Safaeipour, Elham
Poorbaygi, Hosein
Jabbari, Iraj
Sheibani, Shahab
author_sort Safaeipour, Elham
collection PubMed
description (169)Yb has been recently used as an HDR brachytherapy source for cancer treatment. In this paper, dosimetric parameters of a new design of (169)Yb HDR brachytherapy source were determined by Monte Carlo (MC) method and film dosimetry. In this new source, the radioactive core has been encapsulated twice for safety purposes. The calculations of dosimetric parameters carried out using MC simulation in water and air phantom. In order to exclude photon contamination's cutoff energy, δ was set at 10 keV. TG‐43U1 data dosimetric, including S(k), Λ, g(r), F(r, θ) was computed using outputs from the simulation and their statistical uncertainties were calculated. Dose distribution around the new prototype source in PMMA phantom in the framework of AAPM TG‐43 and TG‐55 recommendations was measured by Radiochromic film (RCF) Gafchromic EBT3. Obtained air kerma strength, S(k), and the dose rate constant, Λ, from simulation has a value of 1.03U ± 0.03 and 1.21 cGyh(−1)U(−1) ± 0.03, respectively. The radial dose function was calculated at radial distances between 0.5 and 10 cm with a maximum value of 1.15 ± 0.03 at 5–6 cm distances. The anisotropy functions for radial distances of 0.5–7 cm and angle distances 0° to180° were calculated. The dosimetric data of the new HDR (169)Yb source were compared with another reference source of (169)Yb‐HDR and were found that has acceptable compatibility. In addition, the anisotropy function of the MC simulation and film dosimetry method at a distance of 1 cm from this source was obtained and a good agreement was found between the anisotropy results.
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spelling pubmed-84258582021-09-13 Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source Safaeipour, Elham Poorbaygi, Hosein Jabbari, Iraj Sheibani, Shahab J Appl Clin Med Phys Radiation Oncology Physics (169)Yb has been recently used as an HDR brachytherapy source for cancer treatment. In this paper, dosimetric parameters of a new design of (169)Yb HDR brachytherapy source were determined by Monte Carlo (MC) method and film dosimetry. In this new source, the radioactive core has been encapsulated twice for safety purposes. The calculations of dosimetric parameters carried out using MC simulation in water and air phantom. In order to exclude photon contamination's cutoff energy, δ was set at 10 keV. TG‐43U1 data dosimetric, including S(k), Λ, g(r), F(r, θ) was computed using outputs from the simulation and their statistical uncertainties were calculated. Dose distribution around the new prototype source in PMMA phantom in the framework of AAPM TG‐43 and TG‐55 recommendations was measured by Radiochromic film (RCF) Gafchromic EBT3. Obtained air kerma strength, S(k), and the dose rate constant, Λ, from simulation has a value of 1.03U ± 0.03 and 1.21 cGyh(−1)U(−1) ± 0.03, respectively. The radial dose function was calculated at radial distances between 0.5 and 10 cm with a maximum value of 1.15 ± 0.03 at 5–6 cm distances. The anisotropy functions for radial distances of 0.5–7 cm and angle distances 0° to180° were calculated. The dosimetric data of the new HDR (169)Yb source were compared with another reference source of (169)Yb‐HDR and were found that has acceptable compatibility. In addition, the anisotropy function of the MC simulation and film dosimetry method at a distance of 1 cm from this source was obtained and a good agreement was found between the anisotropy results. John Wiley and Sons Inc. 2021-07-14 /pmc/articles/PMC8425858/ /pubmed/34263515 http://dx.doi.org/10.1002/acm2.13347 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Safaeipour, Elham
Poorbaygi, Hosein
Jabbari, Iraj
Sheibani, Shahab
Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source
title Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source
title_full Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source
title_fullStr Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source
title_full_unstemmed Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source
title_short Evaluation of dosimetric functions for a new (169)Yb HDR Brachytherapy Source
title_sort evaluation of dosimetric functions for a new (169)yb hdr brachytherapy source
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425858/
https://www.ncbi.nlm.nih.gov/pubmed/34263515
http://dx.doi.org/10.1002/acm2.13347
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