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Recent Advances in Ionic Liquids in Biomedicine
The use of ionic liquids and deep eutectic solvents in biomedical applications has grown dramatically in recent years due to their unique properties and their inherent tunability. This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubiliza...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425867/ https://www.ncbi.nlm.nih.gov/pubmed/34245140 http://dx.doi.org/10.1002/advs.202004819 |
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author | Curreri, Alexander M. Mitragotri, Samir Tanner, Eden E. L. |
author_facet | Curreri, Alexander M. Mitragotri, Samir Tanner, Eden E. L. |
author_sort | Curreri, Alexander M. |
collection | PubMed |
description | The use of ionic liquids and deep eutectic solvents in biomedical applications has grown dramatically in recent years due to their unique properties and their inherent tunability. This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of pharmaceuticals through biological barriers, stabilization of proteins and other nucleic acids, antibacterial agents, and development of new biosensors. Current challenges and future outlooks are discussed, including biocompatibility, the potential impact of the presence of impurities, and the importance of understanding the microscopic interactions in ionic liquids in order to design task‐specific solvents. |
format | Online Article Text |
id | pubmed-8425867 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84258672021-09-13 Recent Advances in Ionic Liquids in Biomedicine Curreri, Alexander M. Mitragotri, Samir Tanner, Eden E. L. Adv Sci (Weinh) Reviews The use of ionic liquids and deep eutectic solvents in biomedical applications has grown dramatically in recent years due to their unique properties and their inherent tunability. This review will introduce ionic liquids and deep eutectics and discuss their biomedical applications, namely solubilization of drugs, creation of active pharmaceutical ingredients, delivery of pharmaceuticals through biological barriers, stabilization of proteins and other nucleic acids, antibacterial agents, and development of new biosensors. Current challenges and future outlooks are discussed, including biocompatibility, the potential impact of the presence of impurities, and the importance of understanding the microscopic interactions in ionic liquids in order to design task‐specific solvents. John Wiley and Sons Inc. 2021-07-10 /pmc/articles/PMC8425867/ /pubmed/34245140 http://dx.doi.org/10.1002/advs.202004819 Text en © 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Curreri, Alexander M. Mitragotri, Samir Tanner, Eden E. L. Recent Advances in Ionic Liquids in Biomedicine |
title | Recent Advances in Ionic Liquids in Biomedicine |
title_full | Recent Advances in Ionic Liquids in Biomedicine |
title_fullStr | Recent Advances in Ionic Liquids in Biomedicine |
title_full_unstemmed | Recent Advances in Ionic Liquids in Biomedicine |
title_short | Recent Advances in Ionic Liquids in Biomedicine |
title_sort | recent advances in ionic liquids in biomedicine |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425867/ https://www.ncbi.nlm.nih.gov/pubmed/34245140 http://dx.doi.org/10.1002/advs.202004819 |
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