An MST4‐pβ‐Catenin(Thr40) Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis

Elevated Wnt/β‐catenin signaling has been commonly associated with tumorigenesis especially colorectal cancer (CRC). Here, an MST4‐pβ‐catenin(Thr40) signaling axis essential for intestinal stem cell (ISC) homeostasis and CRC development is uncovered. In response to Wnt3a stimulation, the kinase MST4...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Lin, Moubin, Dong, Chao, Tang, Yang, An, Liwei, Ju, Junyi, Wen, Fuping, Chen, Fan, Wang, Meng, Wang, Wenjia, Chen, Min, Zhao, Yun, Li, Jixi, Hou, Steven X., Lin, Xinhua, Hu, Lulu, Bu, Wenbo, Wu, Dianqing, Li, Lin, Jiao, Shi, Zhou, Zhaocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425901/
https://www.ncbi.nlm.nih.gov/pubmed/34240584
http://dx.doi.org/10.1002/advs.202004850

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