Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

Microglia, the brain’s resident myeloid cells, play central roles in brain defense, homeostasis, and disease. Using a prolonged colony-stimulating factor 1 receptor inhibitor (CSF1Ri) approach, we report an unprecedented level of microglial depletion and establish a model system that achieves an emp...

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Detalles Bibliográficos
Autores principales: Hohsfield, Lindsay A, Najafi, Allison R, Ghorbanian, Yasamine, Soni, Neelakshi, Crapser, Joshua, Figueroa Velez, Dario X, Jiang, Shan, Royer, Sarah E, Kim, Sung Jin, Henningfield, Caden M, Anderson, Aileen, Gandhi, Sunil P, Mortazavi, Ali, Inlay, Matthew A, Green, Kim N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425950/
https://www.ncbi.nlm.nih.gov/pubmed/34423781
http://dx.doi.org/10.7554/eLife.66738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425950/
https://www.ncbi.nlm.nih.gov/pubmed/34423781
http://dx.doi.org/10.7554/eLife.66738

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