Cargando…

Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach

The coronavirus disease 2019 (COVID-19), which emerged in December 2019, continues to be a serious health concern worldwide. There is an urgent need to develop effective drugs and vaccines to control the spread of this disease. In the current study, the main phytochemical compounds of Nigella sativa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mir, Shabir Ahmad, Firoz, Ahmad, Alaidarous, Mohammed, Alshehri, Bader, Bin Dukhyil, Abdul Aziz, Banawas, Saeed, Alsagaby, Suliman A, Alturaiki, Wael, Bhat, Gulzar Ahmad, Kashoo, Faizan, Abdel-Hadi, Ahmad M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426002/ https://www.ncbi.nlm.nih.gov/pubmed/34518755 http://dx.doi.org/10.1016/j.sjbs.2021.09.002

Ejemplares similares

Immunoinformatics-Based Identification of B and T Cell Epitopes in RNA-Dependent RNA Polymerase of SARS-CoV-2
por: Mir, Shabir Ahmad, et al.
Publicado: (2022)

Seroprevalence of Viral Hepatitis B and C among Blood Donors in the Northern Region of Riyadh Province, Saudi Arabia
por: Alqahtani, Saeed Mohammed, et al.
Publicado: (2021)

Prevalence of rheumatoid arthritis and diagnostic validity of a prediction score, in patients visiting orthropedic clinics in the Madinah region of Saudi Arabia: a retrospective cross-sectional study
por: Mir, Shabir Ahmad, et al.
Publicado: (2022)

Inhibitory Potential of the Ocimum sanctum Phytochemicals on Bruton’s Tyrosine Kinase, a Well-Known Drug Target for Treatment of Chronic Lymphocytic Leukemia: An In Silico Investigation
por: Mir, Shabir Ahmad, et al.
Publicado: (2023)

In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia
por: Alsagaby, Suliman A., et al.
Publicado: (2022)

An updated knowledge of Black seed (Nigella sativa Linn.): Review of phytochemical constituents and pharmacological properties
por: Ahmad, Md Faruque, et al.
Publicado: (2021)

Biological Potentials and Phytochemical Constituents of Raw and Roasted Nigella arvensis and Nigella sativa
por: Alshwyeh, Hussah Abdullah, et al.
Publicado: (2022)

Soyasapogenol-B as a Potential Multitarget Therapeutic Agent for Neurodegenerative Disorders: Molecular Docking and Dynamics Study
por: Iqbal, Danish, et al.
Publicado: (2022)

Phytochemical characterization and antimicrobial activity of Nigella sativa seeds
por: Shafodino, Festus S., et al.
Publicado: (2022)

Multidrug-Resistant Bacteria Associated with Cell Phones of Healthcare Professionals in Selected Hospitals in Saudi Arabia
por: Banawas, Saeed, et al.
Publicado: (2018)

Exploring the Binding Pattern of Geraniol with Acetylcholinesterase through In Silico Docking, Molecular Dynamics Simulation, and In Vitro Enzyme Inhibition Kinetics Studies
por: Iqbal, Danish, et al.
Publicado: (2021)

Cardio-protective and anti-cancer therapeutic potential of Nigella sativa
por: Shafiq, Hammad, et al.
Publicado: (2014)

Nobiletin as a Neuroprotectant against NMDA Receptors: An In Silico Approach
por: Jahan, Sadaf, et al.
Publicado: (2022)

Nigella sativa: A Potential Antiosteoporotic Agent
por: Shuid, Ahmad Nazrun, et al.
Publicado: (2012)

A Review on the Cosmeceutical and External Applications of Nigella sativa
por: Eid, Ahmad M., et al.
Publicado: (2017)

Phytochemical Profile and Antioxidant Activity of Nigella sativa L Growing in Morocco
por: Tiji, Salima, et al.
Publicado: (2021)

Seroprevalence of hepatitis B and C viral infections in the premarital adult population of Al Majmaah, Saudi Arabia
por: Mir, Shabir Ahmad, et al.
Publicado: (2021)

Neuroprotective effects of Nigella sativa extracts during germination on central nervous system
por: Islam, Mohammad Hayatul, et al.
Publicado: (2015)

Evaluation of Antioxidant and Antibacterial Potentials of Nigella sativa L. Suspension Cultures under Elicitation
por: Chaudhry, Hera, et al.
Publicado: (2015)

Effect of Nigella sativa Nasal Spray on the Treatment of Chronic Rhinosinusitis Without a Nasal Polyp
por: Rezaeian, Ahmad, et al.
Publicado: (2018)

Safety evaluation of Phytovagex, a pessary formulation of Nigella sativa, on pregnant rats
por: Salarinia, Reza, et al.
Publicado: (2016)

D-Ribose-Induced Glycation and Its Attenuation by the Aqueous Extract of Nigella sativa Seeds
por: Balyan, Prairna, et al.
Publicado: (2022)

High-Throughput Screening and Molecular Dynamics Simulation of Natural Product-like Compounds against Alzheimer’s Disease through Multitarget Approach
por: Iqbal, Danish, et al.
Publicado: (2021)

Effect of Nigella sativa oil on various clinical and biochemical parameters of insulin resistance syndrome
por: Najmi, Ahmad, et al.
Publicado: (2008)

Molecular Mechanisms of Nigella sativa- and Nigella sativa Exercise-Induced Cardiac Hypertrophy in Rats
por: Al Asoom, Lubna Ibrahim
Publicado: (2021)

Plasma levels of BAFF and APRIL are elevated in patients with asthma in Saudi Arabia
por: Alturaiki, Wael, et al.
Publicado: (2021)

Neuropharmacological effects of Nigella sativa
por: Beheshti, Farimah, et al.
Publicado: (2016)

The Immunomodulatory Effect of Nigella sativa
por: Ciesielska-Figlon, Klaudia, et al.
Publicado: (2023)

Antileishmanial Evaluation of Bark Methanolic Extract of Acacia nilotica: In Vitro and In Silico Studies
por: Ali, Rahat, et al.
Publicado: (2021)

Assessment of the Antileishmanial Potential of Cassia fistula Leaf Extract
por: Tabrez, Shams, et al.
Publicado: (2021)

Nobiletin Ameliorates Cellular Damage and Stress Response and Restores Neuronal Identity Altered by Sodium Arsenate Exposure in Human iPSCs-Derived hNPCs
por: Jahan, Sadaf, et al.
Publicado: (2022)

Phytochemical analysis and anti-infective potential of fungal endophytes isolated from Nigella sativa seeds
por: Shady, Nourhan Hisham, et al.
Publicado: (2023)

Effect of sensory integration on attention span among children with infantile hemiplegia
por: Kashoo, Faizan Zaffar, et al.
Publicado: (2019)

Letter to editor
por: Kashoo, Faizan Z., et al.
Publicado: (2020)

Utilization of Nanotechnology to Improve Bone Health in Osteoporosis Exploiting Nigella sativa and Its Active Constituent Thymoquinone
por: Ahmad, Javed, et al.
Publicado: (2022)

Bioactive Compounds of Nigella Sativa Essential Oil as Antibacterial Agents against Chlamydia Trachomatis D
por: Mosolygó, Tímea, et al.
Publicado: (2019)

Proteome Profiling of the Mutagen-Induced Morphological and Yield Macro-Mutant Lines of Nigella sativa L.
por: Asif, Ambreen, et al.
Publicado: (2019)

Bioavailability enhancement studies of amoxicillin with Nigella
por: Ali, Babar, et al.
Publicado: (2012)

Molecular typing of Staphylococcus aureus based on coagulase gene
por: Javid, Faizan, et al.
Publicado: (2018)

SNPs in Mammary Gland Epithelial Cells Unraveling Potential Difference in Milk Production Between Jersey and Kashmiri Cattle Using RNA Sequencing
por: Ahmad, Syed Mudasir, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r0jjc394cs0fs51ie40b2b4s4l