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Incidental prostate-specific membrane antigen-avid meningioma detected on (68)Ga–prostate-specific membrane antigen PET/CT

A 70-year-old gentleman with a history of Gleason score 7 (3 + 4) prostate adenocarcinoma was treated with radical prostatectomy with clear surgical margins. Postoperatively his prostate specific antigen was undetectable. However, his prostate specific antigen was slowly rising and he was referred f...

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Detalles Bibliográficos
Autores principales: Jiang, James Yuheng, Liang Yip, Joshua Wei, Kang, Christine, Tran, Vu Hoang, Lee, Marco Enoch, Le, Ken, Mansberg, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426166/
https://www.ncbi.nlm.nih.gov/pubmed/34522280
http://dx.doi.org/10.1016/j.radcr.2021.08.014
Descripción
Sumario:A 70-year-old gentleman with a history of Gleason score 7 (3 + 4) prostate adenocarcinoma was treated with radical prostatectomy with clear surgical margins. Postoperatively his prostate specific antigen was undetectable. However, his prostate specific antigen was slowly rising and he was referred for a (68)Galium-Prostate Specific Membrane Antigen (PSMA) PET/CT scan. Findings were suggestive of local prostatic cancer recurrence with no evidence of nodal or distant metastasis. An incidental PSMA avid focus was noted in the left frontal lobe, inseparable from the left frontal bone laterally. Subsequent MRI findings were consistent with meningioma. Meningioma is the most common primary brain tumor and may be a cause of false positive prostate cancer metastasis due to (68)Ga-PSMA uptake.