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Potent anti-tumor effects of receptor-retargeted syncytial oncolytic herpes simplex virus
Most oncolytic virotherapy has thus far employed viruses deficient in genes essential for replication in normal cells but not in cancer cells. Intra-tumoral injection of such viruses has resulted in clinically significant anti-tumor effects on the lesions in the vicinity of the injection sites but n...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426171/ https://www.ncbi.nlm.nih.gov/pubmed/34553018 http://dx.doi.org/10.1016/j.omto.2021.08.002 |