E2A ablation enhances proportion of nodal-like cardiomyocytes in cardiac-specific differentiation of human embryonic stem cells

BACKGROUND: Human sinoatrial cardiomyocytes are essential building blocks for cell therapies of conduction system disorders. However, current differentiation protocols for deriving nodal cardiomyocytes from human pluripotent stem cells (hPSCs) are very inefficient. METHODS: By employing the hPSCs to...

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Detalles Bibliográficos
Autores principales: Li, Xiuya, Gao, Fei, Wang, Xiaochen, Liang, Qianqian, Bai, Aobing, Liu, Zhuo, Chen, Xinyun, Li, Ermin, Chen, Sifeng, Lu, Chao, Qian, Ruizhe, Sun, Ning, Liang, Ping, Xu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426208/
https://www.ncbi.nlm.nih.gov/pubmed/34488017
http://dx.doi.org/10.1016/j.ebiom.2021.103575

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