A resource of high-quality and versatile nanobodies for drug delivery

Therapeutic and diagnostic efficacies of small biomolecules and chemical compounds are hampered by suboptimal pharmacokinetics. Here, we developed a repertoire of robust and high-affinity antihuman serum albumin nanobodies (Nb(HSA)) that can be readily fused to small biologics for half-life extensio...

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Detalles Bibliográficos
Autores principales: Shen, Zhuolun, Xiang, Yufei, Vergara, Sandra, Chen, Apeng, Xiao, Zhengyun, Santiago, Ulises, Jin, Changzhong, Sang, Zhe, Luo, Jiadi, Chen, Kong, Schneidman-Duhovny, Dina, Camacho, Carlos, Calero, Guillermo, Hu, Baoli, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426283/
https://www.ncbi.nlm.nih.gov/pubmed/34522857
http://dx.doi.org/10.1016/j.isci.2021.103014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426283/
https://www.ncbi.nlm.nih.gov/pubmed/34522857
http://dx.doi.org/10.1016/j.isci.2021.103014

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