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A resource of high-quality and versatile nanobodies for drug delivery
Therapeutic and diagnostic efficacies of small biomolecules and chemical compounds are hampered by suboptimal pharmacokinetics. Here, we developed a repertoire of robust and high-affinity antihuman serum albumin nanobodies (Nb(HSA)) that can be readily fused to small biologics for half-life extensio...
Autores principales: | Shen, Zhuolun, Xiang, Yufei, Vergara, Sandra, Chen, Apeng, Xiao, Zhengyun, Santiago, Ulises, Jin, Changzhong, Sang, Zhe, Luo, Jiadi, Chen, Kong, Schneidman-Duhovny, Dina, Camacho, Carlos, Calero, Guillermo, Hu, Baoli, Shi, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426283/ https://www.ncbi.nlm.nih.gov/pubmed/34522857 http://dx.doi.org/10.1016/j.isci.2021.103014 |
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