Cargando…

Single-Molecule Insights Into the Dynamics of Replicative Helicases

Helicases are molecular motors that translocate along single-stranded DNA and unwind duplex DNA. They rely on the consumption of chemical energy from nucleotide hydrolysis to drive their translocation. Specialized helicases play a critically important role in DNA replication by unwinding DNA at the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spinks, Richard R., Spenkelink, Lisanne M., Dixon, Nicholas E., van Oijen, Antoine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426354/ https://www.ncbi.nlm.nih.gov/pubmed/34513934 http://dx.doi.org/10.3389/fmolb.2021.741718

Ejemplares similares

DnaB helicase dynamics in bacterial DNA replication resolved by single-molecule studies
por: Spinks, Richard R, et al.
Publicado: (2021)

Observing protein dynamics during DNA-lesion bypass by the replisome
por: Wilkinson, Elise M., et al.
Publicado: (2022)

Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase
por: Whinn, Kelsey S, et al.
Publicado: (2023)

A Toolbox for Site-Specific Labeling of RecQ Helicase With a Single Fluorophore Used in the Single-Molecule Assay
por: Teng, Fang-Yuan, et al.
Publicado: (2020)

New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy
por: Datta, Arindam, et al.
Publicado: (2018)

The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy
por: Seo, Yeon-Soo, et al.
Publicado: (2018)

Searching for DNA Damage: Insights From Single Molecule Analysis
por: Schaich, Matthew A., et al.
Publicado: (2021)

Watching cellular machinery in action, one molecule at a time
por: Monachino, Enrico, et al.
Publicado: (2017)

Decoding Cancer Variants of Unknown Significance for Helicase–Nuclease–RPA Complexes Orchestrating DNA Repair During Transcription and Replication
por: Tsutakawa, Susan E., et al.
Publicado: (2021)

Mechanistic Insight Into Cadmium- and Zinc-Induced Inactivation of the Candida albicans Pif1 Helicase
por: Zhang, Bo, et al.
Publicado: (2022)

Conformational Dynamics of DNA Polymerases Revealed at the Single-Molecule Level
por: Millar, David P.
Publicado: (2022)

Development of a single-stranded DNA-binding protein fluorescent fusion toolbox
por: Dubiel, Katarzyna, et al.
Publicado: (2020)

Single-molecule visualization of fast polymerase turnover in the bacterial replisome
por: Lewis, Jacob S, et al.
Publicado: (2017)

Rapid single-molecule characterisation of enzymes involved in nucleic-acid metabolism
por: Mueller, Stefan H, et al.
Publicado: (2022)

RecQ Helicase Somatic Alterations in Cancer
por: Thakkar, Megha K., et al.
Publicado: (2022)

Single Molecule Study of the Polymerization of RecA on dsDNA: The Dynamics of Individual Domains
por: Maman, Nitzan, et al.
Publicado: (2021)

Recycling of single-stranded DNA-binding protein by the bacterial replisome
por: Spenkelink, Lisanne M, et al.
Publicado: (2019)

Decoding the Structural Dynamics and Conformational Alternations of DNA Secondary Structures by Single-Molecule FRET Microspectroscopy
por: Bandyopadhyay, Debolina, et al.
Publicado: (2021)

The Cellular Functions and Molecular Mechanisms of G-Quadruplex Unwinding Helicases in Humans
por: Liu, Yang, et al.
Publicado: (2021)

Single-Molecule Microscopy Meets Molecular Dynamics Simulations for Characterizing the Molecular Action of Proteins on DNA and in Liquid Condensates
por: Kamagata, Kiyoto
Publicado: (2021)

Corrigendum: The Cellular Functions and Molecular Mechanisms of G-Quadruplex Unwinding Helicases in Humans
por: Liu, Yang, et al.
Publicado: (2022)

Single Molecule Measurements of the Accessibility of Molecular Surfaces
por: Dey, Arpan, et al.
Publicado: (2021)

The Function of Membrane Integral Pyrophosphatases From Whole Organism to Single Molecule
por: Holmes, Alexandra O. M., et al.
Publicado: (2019)

Real-time single-molecule observation of rolling-circle DNA replication
por: Tanner, Nathan A., et al.
Publicado: (2009)

Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System
por: Portlock, Theo J., et al.
Publicado: (2020)

Editorial: Surveying Life One Molecule at a Time: Single Molecule Methods Dig Deeper Into Contemporary Biology
por: Kim, Seong Ho, et al.
Publicado: (2022)

Single-Molecule FRET: A Tool to Characterize DNA Nanostructures
por: Pal, Nibedita
Publicado: (2022)

Mammalian Resilience Revealed by a Comparison of Human Diseases and Mouse Models Associated With DNA Helicase Deficiencies
por: Kohzaki, Masaoki
Publicado: (2022)

Allosterically Linked Binding Sites in Serotonin Transporter Revealed by Single Molecule Force Spectroscopy
por: Zhu, Rong, et al.
Publicado: (2020)

Enhanced UnaG With Minimal Labeling Artifact for Single-Molecule Localization Microscopy
por: Ko, Sangyoon, et al.
Publicado: (2021)

Editorial: Structural biology of nucleic acid replication, recombination and repair
por: Bolt, Edward L., et al.
Publicado: (2023)

Stability versus exchange: a paradox in DNA replication
por: Åberg, Christoffer, et al.
Publicado: (2016)

Next Generation Methods for Single-Molecule Force Spectroscopy on Polyproteins and Receptor-Ligand Complexes
por: Yang, Byeongseon, et al.
Publicado: (2020)

Thermal titration molecular dynamics (TTMD): shedding light on the stability of RNA-small molecule complexes
por: Dodaro, Andrea, et al.
Publicado: (2023)

Molecular Brightness Approach for FRET Analysis of Donor-Linker-Acceptor Constructs at the Single Molecule Level: A Concept
por: Kay, Taryn M., et al.
Publicado: (2021)

Molecular Level Insights Into the Structural and Dynamic Factors Driving Cytokine Function
por: Cui, Jennifer Y., et al.
Publicado: (2021)

Structural Insights Into Tautomeric Dynamics in Nucleic Acids and in Antiviral Nucleoside Analogs
por: Fedeles, Bogdan I., et al.
Publicado: (2022)

Rad5 participates in lesion bypass through its Rev1-binding and ubiquitin ligase domains, but not through its helicase function
por: Masłowska, Katarzyna H., et al.
Publicado: (2022)

BLM Sumoylation Is Required for Replication Stability and Normal Fork Velocity During DNA Replication
por: de Renty, Christelle, et al.
Publicado: (2022)

Determining Trap Compliances, Microsphere Size Variations, and Response Linearities in Single DNA Molecule Elasticity Measurements with Optical Tweezers
por: Mo, Youbin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5ecfreh7rla3tqf70qd91u0gag