Rational design of a nanoparticle platform for oral prophylactic immunotherapy to prevent immunogenicity of therapeutic proteins

The safety and efficacy of several life-saving therapeutic proteins are compromised due to their immunogenicity. Once a sustained immune response against a protein-based therapy is established, clinical options that are safe and cost-effective become limited. Prevention of immunogenicity of therapeu...

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Detalles Bibliográficos
Autores principales: Nguyen, Nhan H., Glassman, Fiona Y., Dingman, Robert K., Shenoy, Gautam N., Wohlfert, Elizabeth A., Kay, Jason G., Bankert, Richard B., Balu-Iyer, Sathy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426360/
https://www.ncbi.nlm.nih.gov/pubmed/34497305
http://dx.doi.org/10.1038/s41598-021-97333-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426360/
https://www.ncbi.nlm.nih.gov/pubmed/34497305
http://dx.doi.org/10.1038/s41598-021-97333-0

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