The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet

Obesity and diabetes increase the risk of arrhythmia and sudden cardiac death. However, the molecular mechanisms of arrhythmia caused by metabolic abnormalities are not well understood. We hypothesized that mitochondrial dysfunction caused by high fat diet (HFD) promotes ventricular arrhythmia. Base...

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Detalles Bibliográficos
Autores principales: Joseph, Leroy C., Reyes, Michael V., Homan, Edwin A., Gowen, Blake, Avula, Uma Mahesh R., Goulbourne, Chris N., Wan, Elaine Y., Elrod, John W., Morrow, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426388/
https://www.ncbi.nlm.nih.gov/pubmed/34497331
http://dx.doi.org/10.1038/s41598-021-97449-3

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