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Monocyte-derived and M1 macrophages from ankylosing spondylitis patients released higher TNF-α and expressed more IL1B in response to BzATP than macrophages from healthy subjects

Macrophages participate in the pathogenesis of ankylosing spondylitis (AS) by producing inflammatory cytokines. Extracellular adenosine triphosphate (eATP), released during cell stress, acts through purinergic receptors (P2XR and P2YR) and induces inflammatory responses. We investigated the effect o...

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Detalles Bibliográficos
Autores principales:	Akhtari, Maryam, Zargar, Seyed Jalal, Vojdanian, Mahdi, Jamshidi, Ahmadreza, Mahmoudi, Mahdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426480/ https://www.ncbi.nlm.nih.gov/pubmed/34497300 http://dx.doi.org/10.1038/s41598-021-96262-2

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