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Activation of gene expression by detergent-like protein domains

The mechanisms by which transcriptional activation domains (tADs) initiate eukaryotic gene expression have been an enigma for decades because most tADs lack specificity in sequence, structure, and interactions with targets. Machine learning analysis of data sets of tAD sequences generated in vivo el...

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Detalles Bibliográficos
Autores principales: Broyles, Bradley K., Gutierrez, Andrew T., Maris, Theodore P., Coil, Daniel A., Wagner, Thomas M., Wang, Xiao, Kihara, Daisuke, Class, Caleb A., Erkine, Alexandre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426559/
https://www.ncbi.nlm.nih.gov/pubmed/34522860
http://dx.doi.org/10.1016/j.isci.2021.103017