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Evaluation of Histone Deacetylase Inhibitors as Radiosensitizers for Proton and Light Ion Radiotherapy

Significant opportunities remain for pharmacologically enhancing the clinical effectiveness of proton and carbon ion-based radiotherapies to achieve both tumor cell radiosensitization and normal tissue radioprotection. We investigated whether pretreatment with the hydroxamate-based histone deacetyla...

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Detalles Bibliográficos
Autores principales: Johnson, Alicia M., Bennett, Paula V., Sanidad, Katherine Z., Hoang, Anthony, Jardine, James H., Keszenman, Deborah J., Wilson, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426582/
https://www.ncbi.nlm.nih.gov/pubmed/34513712
http://dx.doi.org/10.3389/fonc.2021.735940

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