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Tricin Biosynthesis and Bioengineering
Tricin (3',5'-dimethoxyflavone) is a specialized metabolite which not only confers stress tolerance and involves in defense responses in plants but also represents a promising nutraceutical. Tricin-type metabolites are widely present as soluble tricin O-glycosides and tricin-oligolignols i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426635/ https://www.ncbi.nlm.nih.gov/pubmed/34512707 http://dx.doi.org/10.3389/fpls.2021.733198 |
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author | Lam, Pui Ying Lui, Andy C. W. Wang, Lanxiang Liu, Hongjia Umezawa, Toshiaki Tobimatsu, Yuki Lo, Clive |
author_facet | Lam, Pui Ying Lui, Andy C. W. Wang, Lanxiang Liu, Hongjia Umezawa, Toshiaki Tobimatsu, Yuki Lo, Clive |
author_sort | Lam, Pui Ying |
collection | PubMed |
description | Tricin (3',5'-dimethoxyflavone) is a specialized metabolite which not only confers stress tolerance and involves in defense responses in plants but also represents a promising nutraceutical. Tricin-type metabolites are widely present as soluble tricin O-glycosides and tricin-oligolignols in all grass species examined, but only show patchy occurrences in unrelated lineages in dicots. More strikingly, tricin is a lignin monomer in grasses and several other angiosperm species, representing one of the “non-monolignol” lignin monomers identified in nature. The unique biological functions of tricin especially as a lignin monomer have driven the identification and characterization of tricin biosynthetic enzymes in the past decade. This review summarizes the current understanding of tricin biosynthetic pathway in grasses and tricin-accumulating dicots. The characterized and potential enzymes involved in tricin biosynthesis are highlighted along with discussion on the debatable and uncharacterized steps. Finally, current developments of bioengineering on manipulating tricin biosynthesis toward the generation of functional food as well as modifications of lignin for improving biorefinery applications are summarized. |
format | Online Article Text |
id | pubmed-8426635 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84266352021-09-10 Tricin Biosynthesis and Bioengineering Lam, Pui Ying Lui, Andy C. W. Wang, Lanxiang Liu, Hongjia Umezawa, Toshiaki Tobimatsu, Yuki Lo, Clive Front Plant Sci Plant Science Tricin (3',5'-dimethoxyflavone) is a specialized metabolite which not only confers stress tolerance and involves in defense responses in plants but also represents a promising nutraceutical. Tricin-type metabolites are widely present as soluble tricin O-glycosides and tricin-oligolignols in all grass species examined, but only show patchy occurrences in unrelated lineages in dicots. More strikingly, tricin is a lignin monomer in grasses and several other angiosperm species, representing one of the “non-monolignol” lignin monomers identified in nature. The unique biological functions of tricin especially as a lignin monomer have driven the identification and characterization of tricin biosynthetic enzymes in the past decade. This review summarizes the current understanding of tricin biosynthetic pathway in grasses and tricin-accumulating dicots. The characterized and potential enzymes involved in tricin biosynthesis are highlighted along with discussion on the debatable and uncharacterized steps. Finally, current developments of bioengineering on manipulating tricin biosynthesis toward the generation of functional food as well as modifications of lignin for improving biorefinery applications are summarized. Frontiers Media S.A. 2021-08-26 /pmc/articles/PMC8426635/ /pubmed/34512707 http://dx.doi.org/10.3389/fpls.2021.733198 Text en Copyright © 2021 Lam, Lui, Wang, Liu, Umezawa, Tobimatsu and Lo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Plant Science Lam, Pui Ying Lui, Andy C. W. Wang, Lanxiang Liu, Hongjia Umezawa, Toshiaki Tobimatsu, Yuki Lo, Clive Tricin Biosynthesis and Bioengineering |
title | Tricin Biosynthesis and Bioengineering |
title_full | Tricin Biosynthesis and Bioengineering |
title_fullStr | Tricin Biosynthesis and Bioengineering |
title_full_unstemmed | Tricin Biosynthesis and Bioengineering |
title_short | Tricin Biosynthesis and Bioengineering |
title_sort | tricin biosynthesis and bioengineering |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426635/ https://www.ncbi.nlm.nih.gov/pubmed/34512707 http://dx.doi.org/10.3389/fpls.2021.733198 |
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