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α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. α(V)β(6) Integrin may be an intriguing target not only for t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426704/ https://www.ncbi.nlm.nih.gov/pubmed/34132013 http://dx.doi.org/10.1002/cbic.202100209 |
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author | Bugatti, Kelly |
author_facet | Bugatti, Kelly |
author_sort | Bugatti, Kelly |
collection | PubMed |
description | The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. α(V)β(6) Integrin may be an intriguing target not only for the inhibition of SARS‐CoV‐2 entry, but also for the diagnosis/treatment of COVID‐19 related fibrosis, an emerging type of fibrotic disease which will probably affect a significant part of the recovered patients. In this short article, the possible role of this integrin for fighting COVID‐19 is discussed on the basis of recently published evidence, showing how its underestimated involvement may be interesting for the development of novel pharmacological tools. |
format | Online Article Text |
id | pubmed-8426704 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84267042021-09-09 α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases Bugatti, Kelly Chembiochem Viewpoints The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. α(V)β(6) Integrin may be an intriguing target not only for the inhibition of SARS‐CoV‐2 entry, but also for the diagnosis/treatment of COVID‐19 related fibrosis, an emerging type of fibrotic disease which will probably affect a significant part of the recovered patients. In this short article, the possible role of this integrin for fighting COVID‐19 is discussed on the basis of recently published evidence, showing how its underestimated involvement may be interesting for the development of novel pharmacological tools. John Wiley and Sons Inc. 2021-06-15 2021-08-03 /pmc/articles/PMC8426704/ /pubmed/34132013 http://dx.doi.org/10.1002/cbic.202100209 Text en © 2021 The Authors. ChemBioChem published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Viewpoints Bugatti, Kelly α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases |
title | α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases |
title_full | α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases |
title_fullStr | α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases |
title_full_unstemmed | α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases |
title_short | α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases |
title_sort | α(v)β(6) integrin: an intriguing target for covid‐19 and related diseases |
topic | Viewpoints |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426704/ https://www.ncbi.nlm.nih.gov/pubmed/34132013 http://dx.doi.org/10.1002/cbic.202100209 |
work_keys_str_mv | AT bugattikelly avb6integrinanintriguingtargetforcovid19andrelateddiseases |