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α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases

The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. α(V)β(6) Integrin may be an intriguing target not only for t...

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Detalles Bibliográficos
Autor principal: Bugatti, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426704/
https://www.ncbi.nlm.nih.gov/pubmed/34132013
http://dx.doi.org/10.1002/cbic.202100209
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author Bugatti, Kelly
author_facet Bugatti, Kelly
author_sort Bugatti, Kelly
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description The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. α(V)β(6) Integrin may be an intriguing target not only for the inhibition of SARS‐CoV‐2 entry, but also for the diagnosis/treatment of COVID‐19 related fibrosis, an emerging type of fibrotic disease which will probably affect a significant part of the recovered patients. In this short article, the possible role of this integrin for fighting COVID‐19 is discussed on the basis of recently published evidence, showing how its underestimated involvement may be interesting for the development of novel pharmacological tools.
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spelling pubmed-84267042021-09-09 α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases Bugatti, Kelly Chembiochem Viewpoints The outbreak of SARS‐CoV‐2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. α(V)β(6) Integrin may be an intriguing target not only for the inhibition of SARS‐CoV‐2 entry, but also for the diagnosis/treatment of COVID‐19 related fibrosis, an emerging type of fibrotic disease which will probably affect a significant part of the recovered patients. In this short article, the possible role of this integrin for fighting COVID‐19 is discussed on the basis of recently published evidence, showing how its underestimated involvement may be interesting for the development of novel pharmacological tools. John Wiley and Sons Inc. 2021-06-15 2021-08-03 /pmc/articles/PMC8426704/ /pubmed/34132013 http://dx.doi.org/10.1002/cbic.202100209 Text en © 2021 The Authors. ChemBioChem published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Viewpoints
Bugatti, Kelly
α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
title α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
title_full α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
title_fullStr α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
title_full_unstemmed α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
title_short α(V)β(6) Integrin: An Intriguing Target for COVID‐19 and Related Diseases
title_sort α(v)β(6) integrin: an intriguing target for covid‐19 and related diseases
topic Viewpoints
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426704/
https://www.ncbi.nlm.nih.gov/pubmed/34132013
http://dx.doi.org/10.1002/cbic.202100209
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