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Uterine mesenchymal tumors harboring ALK fusions and response to ALK-targeted therapy

Inflammatory myofibroblastic tumor (IMT) of the uterus is a rare but aggressive malignancy that is often misdiagnosed. Approximately 50% of uterine IMTs (UMT) harbor rearrangements involving the ALK gene on chromosome 2p23 with subsequent overexpression of the ALK protein. Molecular characterization...

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Detalles Bibliográficos
Autores principales:	Kyi, Chrisann, Friedman, Claire F., Mueller, Jennifer J., Benayed, Ryma, Ladanyi, Marc, Arcila, Maria, Yang, Soo Ryum, Hensley, Martee L., Chiang, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Case Reports and Case Series
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427213/ https://www.ncbi.nlm.nih.gov/pubmed/34522753 http://dx.doi.org/10.1016/j.gore.2021.100852

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