Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)

Intestinal cancers are developed from intestinal epithelial stem cells (ISCs) in intestinal crypts through a multi-step process involved in genetic mutations of oncogenes and tumor suppressor genes. ISCs play a key role in maintaining the homeostasis of gut epithelium. In 2009, Sato et al establishe...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xiaoxing, Li, Zhaoxia, Zhang, Hongyu, He, Fang, Qiao, Min, Luo, Huaxiu, Zhang, Jing, Zhang, Meng, Mao, Yukun, Wagstaff, William, Zhang, Yongtao, Niu, Changchun, Zhao, Xia, Wang, Hao, Huang, Linjuan, Shi, Deyao, Liu, Qing, Ni, Na, Fu, Kai, Haydon, Rex C., Reid, Russell R., Luu, Hue H., He, Tong-Chuan, Wang, Ziwei, Liang, Houjie, Zhang, Bing-Qiang, Wang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427244/
https://www.ncbi.nlm.nih.gov/pubmed/34522710
http://dx.doi.org/10.1016/j.gendis.2021.01.004

Ejemplares similares

Ejemplares similares