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PTPN18 promotes colorectal cancer progression by regulating the c-MYC-CDK4 axis

Protein tyrosine phosphatase non-receptor type 18 (PTPN18) is often highly expressed in colorectal cancer (CRC), but its role in this disease remains unclear. We demonstrated that PTPN18 overexpression promotes growth and tumorigenesis in CRC cells and that PTPN18 deficiency yields the opposite resu...

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Detalles Bibliográficos
Autores principales:	Li, Chao, Li, Shang-Ze, Huang, Xi-Cheng, Chen, Jie, Liu, Wenbin, Zhang, Xiao-Dong, Song, Xue-Min, Du, Run-Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chongqing Medical University 2020
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427258/ https://www.ncbi.nlm.nih.gov/pubmed/34522712 http://dx.doi.org/10.1016/j.gendis.2020.08.001

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