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CMTM3 suppresses bone formation and osteogenic differentiation of mesenchymal stem cells through inhibiting Erk1/2 and RUNX2 pathways

Osteoporosis, fracture, large-scale craniofacial defects and osteonecrosis are hot topics and are still underdiagnosed and undertreated in the clinic. It is urgent to understand the molecular mechanisms corresponding to the regulation of bone formation. CMTM3 (CKLF-like MARVEL transmembrane domain c...

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Detalles Bibliográficos
Autores principales: Fan, Dongwei, Fan, Daoyang, Yuan, Wanqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427260/
https://www.ncbi.nlm.nih.gov/pubmed/34522715
http://dx.doi.org/10.1016/j.gendis.2020.12.003