Cargando…

Copy Number Signatures and Clinical Outcomes in Upper Tract Urothelial Carcinoma

Tumor staging of upper tract urothelial carcinomas (UTUCs) is relatively difficult to assert accurately before surgery. Here, we used copy number (CN) signatures as a tool to explore their clinical significance of molecular stratification in UTUC. CN signatures were extracted by non-negative matrix...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guan, Bao, Liang, Yuan, Lu, Huan, Xu, Zhengzheng, Shi, Yue, Li, Juan, Kong, Wenwen, Tian, Chuanyu, Tan, Yezhen, Gong, Yanqing, Liu, Jin, Fang, Dong, Shen, Qi, He, Shiming, Shakeel, Muhammad, Zhang, Zhongyuan, He, Qun, Li, Xuesong, Ci, Weimin, Zhou, Liqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427613/ https://www.ncbi.nlm.nih.gov/pubmed/34513842 http://dx.doi.org/10.3389/fcell.2021.713499

Ejemplares similares

Aristolochic acid mutational signature defines the low-risk subtype in upper tract urothelial carcinoma
por: Lu, Huan, et al.
Publicado: (2020)

Identification of Germline Mutations in Upper Tract Urothelial Carcinoma With Suspected Lynch Syndrome
por: Guan, Bao, et al.
Publicado: (2022)

Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients
por: Xiong, Gengyan, et al.
Publicado: (2018)

Contralateral upper tract urothelial carcinoma after nephroureterectomy: the predictive role of DNA methylation
por: Zhang, Lei, et al.
Publicado: (2015)

Positive urinary fluorescence in situ hybridization indicates poor prognosis in patients with upper tract urothelial carcinoma
por: Guan, Bao, et al.
Publicado: (2018)

Increased Expression Of SOX2 Predicts A Poor Prognosis And Promotes Malignant Phenotypes In Upper Tract Urothelial Carcinoma
por: Bao, Zhengqing, et al.
Publicado: (2019)

Single-cell atlases link macrophages and CD8(+) T-cell subpopulations to disease progression and immunotherapy response in urothelial carcinoma
por: Liang, Yuan, et al.
Publicado: (2022)

AB162. Prognostic and predictive value of epigenetic biomarkers and clinical factors in upper tract urothelial carcinoma
por: Xiong, Gengyan, et al.
Publicado: (2015)

High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center
por: Li, Yifan, et al.
Publicado: (2019)

Comparison of clinicopathologic characteristics, epigenetic biomarkers and prognosis between renal pelvic and ureteral tumors in upper tract urothelial carcinoma
por: Fang, Dong, et al.
Publicado: (2018)

Risk Factors for Unfavorable Pathological Types of Intravesical Recurrence in Patients With Upper Urinary Tract Urothelial Carcinoma Following Radical Nephroureterectomy
por: Zhu, Jun, et al.
Publicado: (2022)

Patient‐Derived Upper Tract Urothelial Carcinoma Organoids as a Platform for Drug Screening
por: Li, Zhichao, et al.
Publicado: (2021)

Comparison between completely and traditionally retroperitoneoscopic nephroureterectomy for upper tract urothelial cancer
por: Yao, Lin, et al.
Publicado: (2016)

AB90. Contralateral upper tract urothelial carcinoma after nephroureterectomy: the predictive role of methylation status
por: Zhang, Lei, et al.
Publicado: (2014)

The Influence of Tumor Size on Oncologic Outcomes for Patients with Upper Tract Urothelial Carcinoma after Radical Nephroureterectomy
por: Su, Xiaohong, et al.
Publicado: (2016)

AB93. Prognostic and predictive value of epigenetic biomarkers in upper tract urothelial carcinoma: a large-scale multi-gene promoter methylation analysis
por: Xiong, Gengyan, et al.
Publicado: (2014)

Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma
por: Su, Xiaohong, et al.
Publicado: (2017)

UCseek: ultrasensitive early detection and recurrence monitoring of urothelial carcinoma by shallow-depth genome-wide bisulfite sequencing of urinary sediment DNA
por: Wang, Ping, et al.
Publicado: (2023)

Construction of diagnostic and subtyping models for renal cell carcinoma by genome-wide DNA methylation profiles
por: Zhang, Jianye, et al.
Publicado: (2021)

Copy number gain of ACTN4 is associated with poor prognosis in patients with upper urinary tract urothelial carcinoma
por: Kawamura, Kazuki, et al.
Publicado: (2023)

High expression of KPNA2 defines poor prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy
por: Shi, Bentao, et al.
Publicado: (2015)

AB063. Comparisons of prognosis between urothelial carcinoma of the upper urinary tract and bladder with pT3-4 diseases
por: Su, Xiaohong, et al.
Publicado: (2016)

AB121. The prognostic impact of squamous and glandular differentiation for upper tract urothelial carcinoma patients after radical nephroureterectomy
por: Tang, Qi, et al.
Publicado: (2015)

Role of lymph node dissection in the management of upper tract urothelial carcinomas: a meta-analysis
por: Guo, Runqi, et al.
Publicado: (2018)

Mutations and Copy Number Abnormalities of Hippo Pathway Components in Human Cancers
por: He, Zhengjin, et al.
Publicado: (2021)

DNA methylation subtypes guiding prognostic assessment and linking to responses the DNA methyltransferase inhibitor SGI-110 in urothelial carcinoma
por: Li, Juan, et al.
Publicado: (2022)

AB113. Comparisons of prognosis between urothelial carcinoma of the upper urinary tract and bladder with pT3-4 diseases
por: Su, Xiaohong, et al.
Publicado: (2015)

AB87. Evaluating the impact of preoperative anemia on the prognosis of upper tract urothelial carcinoma following radical nephroureterectomy
por: Xing, Yunchao, et al.
Publicado: (2014)

AB133. Predictive factors for worse pathological outcomes of upper tract urothelial carcinoma: experience from a nationwide high volume center of China
por: Xiong, Gengyan, et al.
Publicado: (2014)

A Novel Preoperative Prediction Model Based on Deep Learning to Predict Neoplasm T Staging and Grading in Patients with Upper Tract Urothelial Carcinoma
por: He, Yuhui, et al.
Publicado: (2022)

AB92. Prevalence and factors associated with baseline chronic kidney disease in China: a 10-year study of 785 upper urinary tract urothelial carcinoma patients
por: Xiong, Gengyan, et al.
Publicado: (2014)

Pattern and risk factors of local recurrence after nephroureterectomy for upper tract urothelial carcinoma
por: Li, Xiaoying, et al.
Publicado: (2020)

Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
por: Tang, Qi, et al.
Publicado: (2023)

Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma
por: Zhan, Yonghao, et al.
Publicado: (2017)

Impact of aristolochic acid exposure on oncologic outcomes of upper tract urothelial carcinoma after radical nephroureterectomy
por: Zhong, Wenlong, et al.
Publicado: (2017)

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma
por: Zhan, Yonghao, et al.
Publicado: (2023)

Surgical techniques and oncological outcomes of pure transperitoneal laparoscopic radical nephroureterectomy for upper urinary tract urothelial carcinoma
por: Yuan, Changwei, et al.
Publicado: (2023)

Nomogram Predicting Renal Insufficiency after Nephroureterectomy for Upper Tract Urothelial Carcinoma in the Chinese Population: Exclusion of Ineligible Candidates for Adjuvant Chemotherapy
por: Fang, Dong, et al.
Publicado: (2014)

Multiparametric Magnetic Resonance Imaging-based Prostate Specific Antigen Density and PI-RADSv2 score help identify Apical Prostate Cancer
por: Huang, Cong, et al.
Publicado: (2023)

Ascorbic acid induced TET2 enzyme activation enhances cancer immunotherapy efficacy in renal cell carcinoma
por: Peng, Ding, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sak84pqqt5vh9hudd5m31cc82t