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Acute Detubulation of Ventricular Myocytes Amplifies the Inhibitory Effect of Cholinergic Agonist on Intracellular Ca(2+) Transients

Muscarinic receptors expressed in cardiac myocytes play a critical role in the regulation of heart function by the parasympathetic nervous system. How the structural organization of cardiac myocytes affects the regulation of Ca(2+) handling by muscarinic receptors is not well-defined. Using confocal...

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Detalles Bibliográficos
Autores principales: Belevych, Andriy E., Bogdanov, Vladimir, Terentyev, Dmitry A., Gyorke, Sandor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427700/
https://www.ncbi.nlm.nih.gov/pubmed/34512394
http://dx.doi.org/10.3389/fphys.2021.725798