Cargando…

Acute Detubulation of Ventricular Myocytes Amplifies the Inhibitory Effect of Cholinergic Agonist on Intracellular Ca(2+) Transients

Muscarinic receptors expressed in cardiac myocytes play a critical role in the regulation of heart function by the parasympathetic nervous system. How the structural organization of cardiac myocytes affects the regulation of Ca(2+) handling by muscarinic receptors is not well-defined. Using confocal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belevych, Andriy E., Bogdanov, Vladimir, Terentyev, Dmitry A., Gyorke, Sandor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427700/ https://www.ncbi.nlm.nih.gov/pubmed/34512394 http://dx.doi.org/10.3389/fphys.2021.725798

Ejemplares similares

Dietary Omega-3 Fatty Acids Promote Arrhythmogenic Remodeling of Cellular Ca(2+) Handling in a Postinfarction Model of Sudden Cardiac Death
por: Belevych, Andriy E., et al.
Publicado: (2013)

The role of luminal Ca regulation in Ca signaling refractoriness and cardiac arrhythmogenesis
por: Györke, Sándor, et al.
Publicado: (2017)

Impact of detubulation on force and kinetics of cardiac muscle contraction
por: Ferrantini, Cecilia, et al.
Publicado: (2014)

T‐tubule recovery after detubulation in isolated mouse cardiomyocytes
por: Tamkus, Greta, et al.
Publicado: (2023)

Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1‐mediated calcium entry in heart failure
por: Baine, Stephen, et al.
Publicado: (2021)

Density and distribution of tetrodotoxin receptors in normal and detubulated frog sartorius muscle
Publicado: (1976)

The role of calcium homeostasis remodeling in inherited cardiac arrhythmia syndromes
por: Hamilton, Shanna, et al.
Publicado: (2021)

Ero1α-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia
por: Hamilton, Shanna, et al.
Publicado: (2022)

Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS
por: Hamilton, Shanna, et al.
Publicado: (2020)

Synchronization of Intracellular Ca(2+) Release in Multicellular Cardiac Preparations
por: Slabaugh, Jessica L., et al.
Publicado: (2018)

Distributed synthesis of sarcolemmal and sarcoplasmic reticulum membrane proteins in cardiac myocytes
por: Bogdanov, Vladimir, et al.
Publicado: (2021)

Effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients
por: Zhang, Chen, et al.
Publicado: (2014)

Modulation of the Local SR Ca(2+) Release by Intracellular Mg(2+) in Cardiac Myocytes
por: Gusev, Konstantin, et al.
Publicado: (2008)

MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex
por: Belevych, Andriy E., et al.
Publicado: (2011)

Hippocampal CA1 Ripples as Inhibitory Transients
por: Malerba, Paola, et al.
Publicado: (2016)

Evaluation of Changes in Morphology and Function of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HiPSC-CMs) Cultured on an Aligned-Nanofiber Cardiac Patch
por: Khan, Mahmood, et al.
Publicado: (2015)

Correction: Evaluation of Changes in Morphology and Function of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HiPSC-CMs) Cultured on an Aligned-Nanofiber Cardiac Patch
por: Khan, Mahmood, et al.
Publicado: (2015)

SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release( )
por: Tow, Brian D, et al.
Publicado: (2021)

Anandamide Reduces Intracellular Ca(2+) Concentration through Suppression of Na(+)/Ca(2+) Exchanger Current in Rat Cardiac Myocytes
por: Li, Qian, et al.
Publicado: (2013)

Ibrutinib impairs IGF-1-dependent activation of intracellular Ca handling in isolated mouse ventricular myocytes
por: Tarnowski, Daniel, et al.
Publicado: (2023)

Diesterified Nitrone Rescues Nitroso-Redox Levels and Increases Myocyte Contraction Via Increased SR Ca(2+) Handling
por: Traynham, Christopher J., et al.
Publicado: (2012)

Physiological increases in lactate inhibit intracellular calcium transients, acidify myocytes and decrease force in term pregnant rat myometrium
por: Hanley, Jacqui‐Ann, et al.
Publicado: (2015)

KChIP2 regulates the cardiac Ca(2+) transient and myocyte contractility by targeting ryanodine receptor activity
por: Nassal, Drew M., et al.
Publicado: (2017)

Metabolic Inhibition Induces Transient Increase of L-type Ca(2+) Current in Human and Rat Cardiac Myocytes
por: Treinys, Rimantas, et al.
Publicado: (2019)

Inhibitory Effect of Cinobufagin on L-Type Ca(2+) Currents, Contractility, and Ca(2+) Homeostasis of Isolated Adult Rat Ventricular Myocytes
por: Li, Pinya, et al.
Publicado: (2014)

Effect of Ca(2+) Efflux Pathway Distribution and Exogenous Ca(2+) Buffers on Intracellular Ca(2+) Dynamics in the Rat Ventricular Myocyte: A Simulation Study
por: Pásek, Michal, et al.
Publicado: (2014)

Amplified intracellular Ca(2+) for synergistic anti-tumor therapy of microwave ablation and chemotherapy
por: Dou, Jian-ping, et al.
Publicado: (2019)

No fuzzy space for intracellular Na(+) in healthy ventricular myocytes
por: Sachse, Frank B., et al.
Publicado: (2017)

Aging and CaMKII Alter Intracellular Ca(2+) Transients and Heart Rhythm in Drosophila melanogaster
por: Santalla, Manuela, et al.
Publicado: (2014)

Sexual dimorphism in bidirectional SR-mitochondria crosstalk in ventricular cardiomyocytes
por: Clements, Richard T., et al.
Publicado: (2023)

Influence of the tubular network on the characteristics of calcium transients in cardiac myocytes
por: Marchena, Miquel, et al.
Publicado: (2020)

Altered Intracellular Calcium Homeostasis and Arrhythmogenesis in the Aged Heart
por: Hamilton, Shanna, et al.
Publicado: (2019)

Intracellular Amplifiers of Reactive Oxygen Species Affecting Mitochondria as Radiosensitizers
por: Xu, Hong-Gui, et al.
Publicado: (2021)

Neuronal Na(+) Channels Are Integral Components of Pro-Arrhythmic Na(+)/Ca(2+) Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-Adrenergic Stimulation
por: Radwański, Przemysław B., et al.
Publicado: (2016)

Palmitoylation of the pore-forming subunit of Ca(v)1.2 controls channel voltage sensitivity and calcium transients in cardiac myocytes
por: Kuo, Chien-Wen S., et al.
Publicado: (2023)

6‐Gingerol, an active pungent component of ginger, inhibits L‐type Ca(2+) current, contractility, and Ca(2+) transients in isolated rat ventricular myocytes
por: Han, Xue, et al.
Publicado: (2019)

The effect of 2,5-di-(tert-butyl)-1,4-benzohydroquinone (TBQ) on intracellular Ca(2+) handling in rat ventricular myocytes
por: Miller, L., et al.
Publicado: (2015)

Regulation of Intracellular pH is Altered in Cardiac Myocytes of Ovariectomized Rats
por: Ibañez, Alejandro Martín, et al.
Publicado: (2019)

Allosteric Regulation of Na/Ca Exchange Current by Cytosolic Ca in Intact Cardiac Myocytes
por: Weber, Christopher R., et al.
Publicado: (2001)

A RGS7-CaMKII complex drives myocyte-intrinsic and myocyte-extrinsic mechanisms of chemotherapy-induced cardiotoxicity
por: Basak, Madhuri, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qb5s4cm4454pnvjl19vhhv2sqj