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Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses

Objective: To investigate the safety and efficacy of a vascular prop device for laparoscopic orthotopic kidney transplantation (LOKT) in swine. Material and Methods: Twenty swine were randomly divided into two groups. A vascular prop device was used in the observation (VP) group, and the vein beltiz...

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Autores principales: Zhang, Peng, Han, Xiu-wu, Zhang, Xin, Zhu, Xu-hui, Li, Tao, Li, Yan-sheng, Chen, Yuan-hao, Li, Gao, Han, Long-xi, Zhang, Rong-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427757/
https://www.ncbi.nlm.nih.gov/pubmed/34513914
http://dx.doi.org/10.3389/fsurg.2021.708449
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author Zhang, Peng
Han, Xiu-wu
Zhang, Xin
Zhu, Xu-hui
Li, Tao
Li, Yan-sheng
Chen, Yuan-hao
Li, Gao
Han, Long-xi
Zhang, Rong-jie
author_facet Zhang, Peng
Han, Xiu-wu
Zhang, Xin
Zhu, Xu-hui
Li, Tao
Li, Yan-sheng
Chen, Yuan-hao
Li, Gao
Han, Long-xi
Zhang, Rong-jie
author_sort Zhang, Peng
collection PubMed
description Objective: To investigate the safety and efficacy of a vascular prop device for laparoscopic orthotopic kidney transplantation (LOKT) in swine. Material and Methods: Twenty swine were randomly divided into two groups. A vascular prop device was used in the observation (VP) group, and the vein beltization technique was used in the control (VB) group. The right kidney, as a donor graft, was laparoscopically transplanted to the location of the left kidney after a left nephrectomy. Data on the operative time, venous anastomotic time, vein stenosis, etc., and the survival of the swine in the two groups were recorded. Results: The mean transplant operative time, the mean cold ischemia time, and the venous anastomotic times in the VP group were significantly shorter than those in the VB group. Seven swine in the VP group and three swine in the VB group survived for 7 days. Autopsy results showed the occurrence of one artery stenosis and one vein stenosis in the VP group and one artery stenosis and five vein stenoses in the VB group. The median survival time was 6.25 days for the swine in the VP group and 4.40 days for those in the VB group. Conclusions: The vascular prop device is safe and feasible for LOKT in swine and may accelerate venous anastomosis and ensure the quality of venous anastomotic stoma.
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spelling pubmed-84277572021-09-10 Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses Zhang, Peng Han, Xiu-wu Zhang, Xin Zhu, Xu-hui Li, Tao Li, Yan-sheng Chen, Yuan-hao Li, Gao Han, Long-xi Zhang, Rong-jie Front Surg Surgery Objective: To investigate the safety and efficacy of a vascular prop device for laparoscopic orthotopic kidney transplantation (LOKT) in swine. Material and Methods: Twenty swine were randomly divided into two groups. A vascular prop device was used in the observation (VP) group, and the vein beltization technique was used in the control (VB) group. The right kidney, as a donor graft, was laparoscopically transplanted to the location of the left kidney after a left nephrectomy. Data on the operative time, venous anastomotic time, vein stenosis, etc., and the survival of the swine in the two groups were recorded. Results: The mean transplant operative time, the mean cold ischemia time, and the venous anastomotic times in the VP group were significantly shorter than those in the VB group. Seven swine in the VP group and three swine in the VB group survived for 7 days. Autopsy results showed the occurrence of one artery stenosis and one vein stenosis in the VP group and one artery stenosis and five vein stenoses in the VB group. The median survival time was 6.25 days for the swine in the VP group and 4.40 days for those in the VB group. Conclusions: The vascular prop device is safe and feasible for LOKT in swine and may accelerate venous anastomosis and ensure the quality of venous anastomotic stoma. Frontiers Media S.A. 2021-08-26 /pmc/articles/PMC8427757/ /pubmed/34513914 http://dx.doi.org/10.3389/fsurg.2021.708449 Text en Copyright © 2021 Zhang, Han, Zhang, Zhu, Li, Li, Chen, Li, Han and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Zhang, Peng
Han, Xiu-wu
Zhang, Xin
Zhu, Xu-hui
Li, Tao
Li, Yan-sheng
Chen, Yuan-hao
Li, Gao
Han, Long-xi
Zhang, Rong-jie
Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
title Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
title_full Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
title_fullStr Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
title_full_unstemmed Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
title_short Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
title_sort laparoscopic orthotopic kidney transplantation in swine: a novel vascular prop device for venous anastomoses
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427757/
https://www.ncbi.nlm.nih.gov/pubmed/34513914
http://dx.doi.org/10.3389/fsurg.2021.708449
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