Cargando…
Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses
Objective: To investigate the safety and efficacy of a vascular prop device for laparoscopic orthotopic kidney transplantation (LOKT) in swine. Material and Methods: Twenty swine were randomly divided into two groups. A vascular prop device was used in the observation (VP) group, and the vein beltiz...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427757/ https://www.ncbi.nlm.nih.gov/pubmed/34513914 http://dx.doi.org/10.3389/fsurg.2021.708449 |
_version_ | 1783750236693331968 |
---|---|
author | Zhang, Peng Han, Xiu-wu Zhang, Xin Zhu, Xu-hui Li, Tao Li, Yan-sheng Chen, Yuan-hao Li, Gao Han, Long-xi Zhang, Rong-jie |
author_facet | Zhang, Peng Han, Xiu-wu Zhang, Xin Zhu, Xu-hui Li, Tao Li, Yan-sheng Chen, Yuan-hao Li, Gao Han, Long-xi Zhang, Rong-jie |
author_sort | Zhang, Peng |
collection | PubMed |
description | Objective: To investigate the safety and efficacy of a vascular prop device for laparoscopic orthotopic kidney transplantation (LOKT) in swine. Material and Methods: Twenty swine were randomly divided into two groups. A vascular prop device was used in the observation (VP) group, and the vein beltization technique was used in the control (VB) group. The right kidney, as a donor graft, was laparoscopically transplanted to the location of the left kidney after a left nephrectomy. Data on the operative time, venous anastomotic time, vein stenosis, etc., and the survival of the swine in the two groups were recorded. Results: The mean transplant operative time, the mean cold ischemia time, and the venous anastomotic times in the VP group were significantly shorter than those in the VB group. Seven swine in the VP group and three swine in the VB group survived for 7 days. Autopsy results showed the occurrence of one artery stenosis and one vein stenosis in the VP group and one artery stenosis and five vein stenoses in the VB group. The median survival time was 6.25 days for the swine in the VP group and 4.40 days for those in the VB group. Conclusions: The vascular prop device is safe and feasible for LOKT in swine and may accelerate venous anastomosis and ensure the quality of venous anastomotic stoma. |
format | Online Article Text |
id | pubmed-8427757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84277572021-09-10 Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses Zhang, Peng Han, Xiu-wu Zhang, Xin Zhu, Xu-hui Li, Tao Li, Yan-sheng Chen, Yuan-hao Li, Gao Han, Long-xi Zhang, Rong-jie Front Surg Surgery Objective: To investigate the safety and efficacy of a vascular prop device for laparoscopic orthotopic kidney transplantation (LOKT) in swine. Material and Methods: Twenty swine were randomly divided into two groups. A vascular prop device was used in the observation (VP) group, and the vein beltization technique was used in the control (VB) group. The right kidney, as a donor graft, was laparoscopically transplanted to the location of the left kidney after a left nephrectomy. Data on the operative time, venous anastomotic time, vein stenosis, etc., and the survival of the swine in the two groups were recorded. Results: The mean transplant operative time, the mean cold ischemia time, and the venous anastomotic times in the VP group were significantly shorter than those in the VB group. Seven swine in the VP group and three swine in the VB group survived for 7 days. Autopsy results showed the occurrence of one artery stenosis and one vein stenosis in the VP group and one artery stenosis and five vein stenoses in the VB group. The median survival time was 6.25 days for the swine in the VP group and 4.40 days for those in the VB group. Conclusions: The vascular prop device is safe and feasible for LOKT in swine and may accelerate venous anastomosis and ensure the quality of venous anastomotic stoma. Frontiers Media S.A. 2021-08-26 /pmc/articles/PMC8427757/ /pubmed/34513914 http://dx.doi.org/10.3389/fsurg.2021.708449 Text en Copyright © 2021 Zhang, Han, Zhang, Zhu, Li, Li, Chen, Li, Han and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Zhang, Peng Han, Xiu-wu Zhang, Xin Zhu, Xu-hui Li, Tao Li, Yan-sheng Chen, Yuan-hao Li, Gao Han, Long-xi Zhang, Rong-jie Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses |
title | Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses |
title_full | Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses |
title_fullStr | Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses |
title_full_unstemmed | Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses |
title_short | Laparoscopic Orthotopic Kidney Transplantation in Swine: A Novel Vascular Prop Device for Venous Anastomoses |
title_sort | laparoscopic orthotopic kidney transplantation in swine: a novel vascular prop device for venous anastomoses |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427757/ https://www.ncbi.nlm.nih.gov/pubmed/34513914 http://dx.doi.org/10.3389/fsurg.2021.708449 |
work_keys_str_mv | AT zhangpeng laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT hanxiuwu laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT zhangxin laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT zhuxuhui laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT litao laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT liyansheng laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT chenyuanhao laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT ligao laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT hanlongxi laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses AT zhangrongjie laparoscopicorthotopickidneytransplantationinswineanovelvascularpropdeviceforvenousanastomoses |