Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report

BACKGROUND: Recombinant tissue plasminogen activator (rt-pa) is the first-line drug for the treatment of acute ischemic stroke, and can lead to some complications.There were rare reports of death due to acute pulmonary edema during rt-pa thrombolysis treatment. CASE PRESENTATION: This study reports...

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Autores principales: Chen, Xue-Bing, Qu, Dong, Zhang, Qing, Yue, Xia, Qiao, Dong-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427873/
https://www.ncbi.nlm.nih.gov/pubmed/34503474
http://dx.doi.org/10.1186/s12883-021-02371-w
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author Chen, Xue-Bing
Qu, Dong
Zhang, Qing
Yue, Xia
Qiao, Dong-Fang
author_facet Chen, Xue-Bing
Qu, Dong
Zhang, Qing
Yue, Xia
Qiao, Dong-Fang
author_sort Chen, Xue-Bing
collection PubMed
description BACKGROUND: Recombinant tissue plasminogen activator (rt-pa) is the first-line drug for the treatment of acute ischemic stroke, and can lead to some complications.There were rare reports of death due to acute pulmonary edema during rt-pa thrombolysis treatment. CASE PRESENTATION: This study reports a 30-year-old man was diagnosed with acute ischemic stroke and underwent rt-pa thrombolytic therapy. Finally he died despite active rescue. CONCLUSIONS: The autopsy revealed that he died of acute pulmonary edema. This case suggests that it is necessary to pay close attention to the changes of vital signs during thrombolysis and be aware of possibility of pulmonary edema during thrombolysis.
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spelling pubmed-84278732021-09-10 Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report Chen, Xue-Bing Qu, Dong Zhang, Qing Yue, Xia Qiao, Dong-Fang BMC Neurol Case Report BACKGROUND: Recombinant tissue plasminogen activator (rt-pa) is the first-line drug for the treatment of acute ischemic stroke, and can lead to some complications.There were rare reports of death due to acute pulmonary edema during rt-pa thrombolysis treatment. CASE PRESENTATION: This study reports a 30-year-old man was diagnosed with acute ischemic stroke and underwent rt-pa thrombolytic therapy. Finally he died despite active rescue. CONCLUSIONS: The autopsy revealed that he died of acute pulmonary edema. This case suggests that it is necessary to pay close attention to the changes of vital signs during thrombolysis and be aware of possibility of pulmonary edema during thrombolysis. BioMed Central 2021-09-09 /pmc/articles/PMC8427873/ /pubmed/34503474 http://dx.doi.org/10.1186/s12883-021-02371-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Chen, Xue-Bing
Qu, Dong
Zhang, Qing
Yue, Xia
Qiao, Dong-Fang
Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report
title Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report
title_full Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report
title_fullStr Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report
title_full_unstemmed Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report
title_short Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report
title_sort might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427873/
https://www.ncbi.nlm.nih.gov/pubmed/34503474
http://dx.doi.org/10.1186/s12883-021-02371-w
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