Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent

BACKGROUND: One of the most prominent opioid analgesics in the United States is the high potency agonist fentanyl. It is used in the treatment of acute and chronic pain and as an anesthetic adjuvant. When used inappropriately, however, ingestion of just a few milligrams of fentanyl or other syntheti...

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Detalles Bibliográficos
Autores principales: Hedrick, Sidnee L., Luo, Dan, Kaska, Sophia, Niloy, Kumar Kulldeep, Jackson, Karen, Sarma, Rupam, Horn, Jamie, Baynard, Caroline, Leggas, Markos, Butelman, Eduardo R., Kreek, Mary Jeanne, Prisinzano, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427951/
https://www.ncbi.nlm.nih.gov/pubmed/34503531
http://dx.doi.org/10.1186/s12929-021-00758-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427951/
https://www.ncbi.nlm.nih.gov/pubmed/34503531
http://dx.doi.org/10.1186/s12929-021-00758-y

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