Evaluation of some aspects in supervised cell type identification for single-cell RNA-seq: classifier, feature selection, and reference construction

BACKGROUND: Cell type identification is one of the most important questions in single-cell RNA sequencing (scRNA-seq) data analysis. With the accumulation of public scRNA-seq data, supervised cell type identification methods have gained increasing popularity due to better accuracy, robustness, and c...

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Detalles Bibliográficos
Autores principales: Ma, Wenjing, Su, Kenong, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427961/
https://www.ncbi.nlm.nih.gov/pubmed/34503564
http://dx.doi.org/10.1186/s13059-021-02480-2

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