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Chronic hyponatremia based on maxillary sinus mass

SUMMARY: This is a case report of a child with chronic hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) as a paraneoplastic manifestation of olfactory neuroblastoma (OFN). We hereby report a clinical presentation as well as a pragmatic approach to one of the m...

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Autores principales: Tudor, Darija, Kolombo, Iva, Tot, Ana, Cikojevic, Drasko, Simunovic, Marko, Skrabic, Veselin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428015/
https://www.ncbi.nlm.nih.gov/pubmed/34477110
http://dx.doi.org/10.1530/EDM-21-0068
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author Tudor, Darija
Kolombo, Iva
Tot, Ana
Cikojevic, Drasko
Simunovic, Marko
Skrabic, Veselin
author_facet Tudor, Darija
Kolombo, Iva
Tot, Ana
Cikojevic, Drasko
Simunovic, Marko
Skrabic, Veselin
author_sort Tudor, Darija
collection PubMed
description SUMMARY: This is a case report of a child with chronic hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) as a paraneoplastic manifestation of olfactory neuroblastoma (OFN). We hereby report a clinical presentation as well as a pragmatic approach to one of the most common electrolytic disorders in the pediatric population and have emphasized the necessity of involving the sinonasal area in the diagnostic procedure while evaluating possible causes of SIADH. This report indicates that the chronicity of the process along with the gradual onset of hyponatremia occurrence is responsible for the lack of neurological symptoms at the moment of disease presentation. LEARNING POINTS: Hyponatremia is not infrequently attributed to SIADH. Paraneoplastic syndromes are uncommon but they should be considered in the differential diagnosis of pediatric SIADH. Chronic insidious hyponatremia may not be associated with clear neurological symptoms despite its severity.
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spelling pubmed-84280152021-09-13 Chronic hyponatremia based on maxillary sinus mass Tudor, Darija Kolombo, Iva Tot, Ana Cikojevic, Drasko Simunovic, Marko Skrabic, Veselin Endocrinol Diabetes Metab Case Rep Unique/Unexpected Symptoms or Presentations of a Disease SUMMARY: This is a case report of a child with chronic hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) as a paraneoplastic manifestation of olfactory neuroblastoma (OFN). We hereby report a clinical presentation as well as a pragmatic approach to one of the most common electrolytic disorders in the pediatric population and have emphasized the necessity of involving the sinonasal area in the diagnostic procedure while evaluating possible causes of SIADH. This report indicates that the chronicity of the process along with the gradual onset of hyponatremia occurrence is responsible for the lack of neurological symptoms at the moment of disease presentation. LEARNING POINTS: Hyponatremia is not infrequently attributed to SIADH. Paraneoplastic syndromes are uncommon but they should be considered in the differential diagnosis of pediatric SIADH. Chronic insidious hyponatremia may not be associated with clear neurological symptoms despite its severity. Bioscientifica Ltd 2021-07-13 /pmc/articles/PMC8428015/ /pubmed/34477110 http://dx.doi.org/10.1530/EDM-21-0068 Text en © The authors https://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Unique/Unexpected Symptoms or Presentations of a Disease
Tudor, Darija
Kolombo, Iva
Tot, Ana
Cikojevic, Drasko
Simunovic, Marko
Skrabic, Veselin
Chronic hyponatremia based on maxillary sinus mass
title Chronic hyponatremia based on maxillary sinus mass
title_full Chronic hyponatremia based on maxillary sinus mass
title_fullStr Chronic hyponatremia based on maxillary sinus mass
title_full_unstemmed Chronic hyponatremia based on maxillary sinus mass
title_short Chronic hyponatremia based on maxillary sinus mass
title_sort chronic hyponatremia based on maxillary sinus mass
topic Unique/Unexpected Symptoms or Presentations of a Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428015/
https://www.ncbi.nlm.nih.gov/pubmed/34477110
http://dx.doi.org/10.1530/EDM-21-0068
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