Cargando…

CSF Chitinase 3–Like 2 Is Associated With Long-term Disability Progression in Patients With Progressive Multiple Sclerosis

OBJECTIVE: This study aimed to identify long-term prognostic protein biomarkers associated with disease progression in patients with progressive multiple sclerosis (MS). METHODS: CSF samples were collected from a discovery cohort of 28 patients with progressive MS who participated in a clinical tria...

Descripción completa

Detalles Bibliográficos
Autores principales:	Comabella, Manuel, Sastre-Garriga, Jaume, Borras, Eva, Villar, Luisa M., Saiz, Albert, Martínez-Yélamos, Sergio, García-Merino, Juan Antonio, Pinteac, Rucsanda, Fissolo, Nicolas, Sánchez López, Antonio J., Costa-Frossard, Lucienne, Blanco, Yolanda, Llufriu, Sara, Vidal-Jordana, Angela, Sabidó, Eduard, Montalban, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428018/ https://www.ncbi.nlm.nih.gov/pubmed/34497102 http://dx.doi.org/10.1212/NXI.0000000000001082

Ejemplares similares

Chitinases and chitinase-like proteins as biomarkers in neurologic disorders
por: Pinteac, Rucsanda, et al.
Publicado: (2020)

CSF SERPINA3 Levels Are Elevated in Patients With Progressive MS
por: Fissolo, Nicolás, et al.
Publicado: (2021)

Molecular signature associated with cladribine treatment in patients with multiple sclerosis
por: Fissolo, Nicolas, et al.
Publicado: (2023)

Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non‐cell‐autonomous neuronal damage
por: Matute‐Blanch, Clara, et al.
Publicado: (2022)

CSF chitinase 3-like-1 association with disability of primary progressive MS
por: Pérez-Miralles, Francisco, et al.
Publicado: (2020)

Role of high mobility group box protein 1 (HMGB1) in peripheral blood from patients with multiple sclerosis
por: Malhotra, Sunny, et al.
Publicado: (2015)

Chitinase 3-like 1 is neurotoxic in primary cultured neurons
por: Matute-Blanch, Clara, et al.
Publicado: (2020)

Chitinase-3-like 1-protein in CSF: a novel biomarker for progression in patients with multiple sclerosis
por: Talaat, Foraysa, et al.
Publicado: (2023)

Association of Early Progression Independent of Relapse Activity With Long-term Disability After a First Demyelinating Event in Multiple Sclerosis
por: Tur, Carmen, et al.
Publicado: (2022)

Serum Levels of CXCL13 Are Associated With Teriflunomide Response in Patients With Multiple Sclerosis
por: Fissolo, Nicolás, et al.
Publicado: (2022)

Immunomodulatory Effects Associated with Cladribine Treatment
por: Fissolo, Nicolás, et al.
Publicado: (2021)

Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis
por: Cantó, Ester, et al.
Publicado: (2014)

CSF chitinases before and after symptom onset in amyotrophic lateral sclerosis
por: Gray, Elizabeth, et al.
Publicado: (2020)

Predictive value of early brain atrophy on response in patients treated with interferon β
por: Pérez-Miralles, Francisco Carlos, et al.
Publicado: (2015)

Risk Acceptance in Multiple Sclerosis Patients on Natalizumab Treatment
por: Tur, Carmen, et al.
Publicado: (2013)

Lesion topographies in multiple sclerosis diagnosis: A reappraisal
por: Arrambide, Georgina, et al.
Publicado: (2017)

Revista de Neurología cumple medio siglo
por: Sastre-Garriga, Jaume
Publicado: (2023)

Chitinase 3–like 1 and neurofilament light chain in CSF and CNS atrophy in MS
por: Schneider, Ruth, et al.
Publicado: (2020)

Brain region volumes and their relationship with disability progression and cognitive function in primary progressive multiple sclerosis
por: Pérez‐Miralles, Francisco Carlos, et al.
Publicado: (2021)

Treatment with MOG-DNA vaccines induces CD4(+)CD25(+)FoxP3(+) regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis
por: Fissolo, Nicolás, et al.
Publicado: (2012)

Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer’s disease
por: Moreno-Rodriguez, Marta, et al.
Publicado: (2020)

Circulating EZH2-positive T cells are decreased in multiple sclerosis patients
por: Malhotra, Sunny, et al.
Publicado: (2018)

Perception of stigma in patients with primary progressive multiple sclerosis
por: Pérez-Miralles, Francisco, et al.
Publicado: (2019)

Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course
por: Gil-Varea, Elia, et al.
Publicado: (2018)

Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II alleles
por: de la Hera, Belén, et al.
Publicado: (2014)

T1/T2-weighted ratio in multiple sclerosis: A longitudinal study with clinical associations
por: Boaventura, Mateus, et al.
Publicado: (2022)

A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis
por: Malolepszy, Anna, et al.
Publicado: (2018)

Consensus on early detection of disease progression in patients with multiple sclerosis
por: Meca-Lallana, José E., et al.
Publicado: (2022)

Optic Nerve Topography in Multiple Sclerosis Diagnosis: The Utility of Visual Evoked Potentials
por: Vidal-Jordana, Angela, et al.
Publicado: (2021)

Oral contraceptives do not modify the risk of a second attack and disability accrual in a prospective cohort of women with a clinically isolated syndrome and early multiple sclerosis
por: Otero-Romero, Susana, et al.
Publicado: (2021)

Detection of lesions in the optic nerve with magnetic resonance imaging using a 3D convolutional neural network
por: Martí-Juan, Gerard, et al.
Publicado: (2022)

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
por: He, Kai, et al.
Publicado: (2022)

Progress in CSF biomarker discovery in sCJD
por: Llorens, Franc, et al.
Publicado: (2016)

CSF dynamics as a predictor of cognitive progression
por: Cogswell, Petrice M., et al.
Publicado: (2021)

Neurofilament light chain level is a weak risk factor for the development of MS
por: Arrambide, Georgina, et al.
Publicado: (2016)

CSF CXCL13 and Chitinase 3-like-1 Levels Predict Disease Course in Relapsing Multiple Sclerosis
por: Lucchini, Matteo, et al.
Publicado: (2022)

miRNA Signature in CSF From Patients With Primary Progressive Multiple Sclerosis
por: Muñoz-San Martín, María, et al.
Publicado: (2022)

Baseline Inflammatory Status Reveals Dichotomic Immune Mechanisms Involved In Primary-Progressive Multiple Sclerosis Pathology
por: Fernández-Velasco, José I., et al.
Publicado: (2022)

Chitinases: An update
por: Hamid, Rifat, et al.
Publicado: (2013)

Identification of the Immunological Changes Appearing in the CSF During the Early Immunosenescence Process Occurring in Multiple Sclerosis
por: Picón, Carmen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ps97kq1hqtvodjviu89m5npb9t