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Role of the GH-IGF1 axis on the hypothalamus–pituitary–testicular axis function: lessons from Laron syndrome
BACKGROUND: Animal studies suggest that insulin-like growth factor 1 (IGF1) may influence the function of the hypothalamus–pituitary–testicular axis, especially in childhood, but the evidence in humans is scanty. Laron syndrome, a human model of IGF1 deficiency, may help to solve this issue. PURPOSE...
Autores principales: | Cannarella, Rossella, Crafa, Andrea, La Vignera, Sandro, Condorelli, Rosita A, Calogero, Aldo E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428041/ https://www.ncbi.nlm.nih.gov/pubmed/34319907 http://dx.doi.org/10.1530/EC-21-0252 |
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