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A direct negative feedback loop of miR-4721/FOXA1/Nanog promotes nasopharyngeal cell stem cell enrichment and metastasis

OBJECTIVE: The recurrence and metastasis of nasopharyngeal cancer (NPC) may be mainly attributed to the persistence of cancer stem cells (CSCs); however, the linkage mechanism has yet to be fully elucidated. METHODS: The levels of miR-4721, FOXA1, and Nanog expression in NPC were detected by in situ...

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Detalles Bibliográficos
Autores principales:	Zhao, Mengyang, Tang, Zibo, Wang, Yijun, Ding, Jiaojiao, Guo, Ying, Gao, Tianhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428129/ https://www.ncbi.nlm.nih.gov/pubmed/34503528 http://dx.doi.org/10.1186/s12967-021-03059-y

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