Exome Sequencing Reveals a Putative Role for HLA-C*03:02 in Control of HIV-1 in African Pediatric Populations

Human leucocyte antigen (HLA) class I molecules present endogenously processed antigens to T-cells and have been linked to differences in HIV-1 disease progression. HLA allelotypes show considerable geographical and inter-individual variation, as does the rate of progression of HIV-1 disease, with l...

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Detalles Bibliográficos
Autores principales: Kyobe, Samuel, Mwesigwa, Savannah, Kisitu, Grace P., Farirai, John, Katagirya, Eric, Mirembe, Angella N., Ketumile, Lesego, Wayengera, Misaki, Katabazi, Fred Ashaba, Kigozi, Edgar, Wampande, Edward M., Retshabile, Gaone, Mlotshwa, Busisiwe C., Williams, Lesedi, Morapedi, Koketso, Kasvosve, Ishmael, Kyosiimire-Lugemwa, Jacqueline, Nsangi, Betty, Tsimako-Johnstone, Masego, Brown, Chester W., Joloba, Moses, Anabwani, Gabriel, Bhekumusa, Lukhele, Mpoloka, Sununguko W., Mardon, Graeme, Matshaba, Mogomotsi, Kekitiinwa, Adeodata, Hanchard, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428176/
https://www.ncbi.nlm.nih.gov/pubmed/34512729
http://dx.doi.org/10.3389/fgene.2021.720213

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