Transcriptional Reprogramming and Constitutive PD-L1 Expression in Melanoma Are Associated with Dedifferentiation and Activation of Interferon and Tumour Necrosis Factor Signalling Pathways

SIMPLE SUMMARY: Melanoma, an aggressive form of skin cancer, is frequently associated with drug resistance in the advanced stages. For instance, frequently resistance is observed in sequential treatment of melanoma with targeted therapy and immunotherapy. In this research, the authors investigated w...

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Detalles Bibliográficos
Autores principales: Ahn, Antonio, Rodger, Euan J., Motwani, Jyoti, Gimenez, Gregory, Stockwell, Peter A., Parry, Matthew, Hersey, Peter, Chatterjee, Aniruddha, Eccles, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428231/
https://www.ncbi.nlm.nih.gov/pubmed/34503064
http://dx.doi.org/10.3390/cancers13174250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428231/
https://www.ncbi.nlm.nih.gov/pubmed/34503064
http://dx.doi.org/10.3390/cancers13174250

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