Glutaraldehyde-crosslinked chitosan-polyethylene oxide nanofibers as a potential gastroretentive delivery system of nizatidine for augmented gastroprotective activity

Nizatidine (NIZ), a histamine H(2)-receptor antagonist, is soluble and stable in the stomach, however, it exhibits a short half-life and a rapid clearance. Therefore, chitosan (CS) and polyethylene oxide (PEO) nanofibers (NFs) at different weight ratios were prepared by electrospinning and character...

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Detalles Bibliográficos
Autores principales: Abd El Hady, Walaa Ebrahim, Soliman, Osama Abd El-Aazeem, El Sabbagh, Hassan Mohamed, Mohamed, Elham Abdelmonem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428272/
https://www.ncbi.nlm.nih.gov/pubmed/34470551
http://dx.doi.org/10.1080/10717544.2021.1971796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428272/
https://www.ncbi.nlm.nih.gov/pubmed/34470551
http://dx.doi.org/10.1080/10717544.2021.1971796

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