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Glutaraldehyde-crosslinked chitosan-polyethylene oxide nanofibers as a potential gastroretentive delivery system of nizatidine for augmented gastroprotective activity
Nizatidine (NIZ), a histamine H(2)-receptor antagonist, is soluble and stable in the stomach, however, it exhibits a short half-life and a rapid clearance. Therefore, chitosan (CS) and polyethylene oxide (PEO) nanofibers (NFs) at different weight ratios were prepared by electrospinning and character...
Autores principales: | Abd El Hady, Walaa Ebrahim, Soliman, Osama Abd El-Aazeem, El Sabbagh, Hassan Mohamed, Mohamed, Elham Abdelmonem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428272/ https://www.ncbi.nlm.nih.gov/pubmed/34470551 http://dx.doi.org/10.1080/10717544.2021.1971796 |
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