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Impact of Inhibition of the Mitochondrial Pyruvate Carrier on the Tumor Extracellular pH as Measured by CEST-MRI

SIMPLE SUMMARY: Dysregulated metabolism is a key hallmark of cancer cells and many solid tumors are acidic. Acidosis is responsible for cancer aggressiveness and for resistance to several treatments. In the present study, we evaluated to which extent tumor acidosis was influenced upon inhibition of...

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Detalles Bibliográficos
Autores principales:	Buyse, Chloé, Joudiou, Nicolas, Corbet, Cyril, Feron, Olivier, Mignion, Lionel, Flament, Julien, Gallez, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428345/ https://www.ncbi.nlm.nih.gov/pubmed/34503089 http://dx.doi.org/10.3390/cancers13174278

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