Receptor Switching in Newly Evolved Adeno-associated Viruses

Adeno-associated viruses utilize different glycans and the AAV receptor (AAVR) for cellular attachment and entry. Directed evolution has yielded new AAV variants; however, structure-function correlates underlying their improved transduction are generally overlooked. Here, we report that infectious c...

Descripción completa

Detalles Bibliográficos
Autores principales: Havlik, L. Patrick, Das, Anshuman, Mietzsch, Mario, Oh, Daniel K., Ark, Jonathan, McKenna, Robert, Agbandje-McKenna, Mavis, Asokan, Aravind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428401/
https://www.ncbi.nlm.nih.gov/pubmed/34232726
http://dx.doi.org/10.1128/JVI.00587-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428401/
https://www.ncbi.nlm.nih.gov/pubmed/34232726
http://dx.doi.org/10.1128/JVI.00587-21

Ejemplares similares