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Effects of adding L-arginine orally to standard therapy in patients with COVID-19: A randomized, double-blind, placebo-controlled, parallel-group trial. Results of the first interim analysis
BACKGROUND: We and others have previously demonstrated that the endothelium is a primary target of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and L-arginine has been shown to improve endothelial dysfunction. However, the effects of L-arginine have never been evaluated in coron...
Autores principales: | Fiorentino, Giuseppe, Coppola, Antonietta, Izzo, Raffaele, Annunziata, Anna, Bernardo, Mariano, Lombardi, Angela, Trimarco, Valentina, Santulli, Gaetano, Trimarco, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428476/ https://www.ncbi.nlm.nih.gov/pubmed/34522871 http://dx.doi.org/10.1016/j.eclinm.2021.101125 |
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