Follicular Helper T (T(FH)) Cell Targeting by TLR8 Signaling For Improving HBsAg-Specific B Cell Response In Chronic Hepatitis B Patients

Identifying signaling pathways that induce B cell response can aid functional cure strategies for chronic hepatitis B infection (CHB). TLR8 activation with ssRNA was shown to enhance follicular helper T cell (T(FH)) function leading to improved B cell responses in vitro. We investigated whether this...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayithan, Natarajan, Tang, Lydia, Tan, Susanna K., Chen, Diana, Wallin, Jeffrey J., Fletcher, Simon P., Kottilil, Shyam, Poonia, Bhawna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428528/
https://www.ncbi.nlm.nih.gov/pubmed/34512670
http://dx.doi.org/10.3389/fimmu.2021.735913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428528/
https://www.ncbi.nlm.nih.gov/pubmed/34512670
http://dx.doi.org/10.3389/fimmu.2021.735913

Ejemplares similares