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Similar quality in chronic kidney disease multidisciplinary follow-up between kidney

INTRODUCTION: Multidisciplinary clinics are the best approach towards Chronic Kidney Disease (CKD) patients in pre-dialysis phases. The few studies regarding kidney transplant recipients (KTR) compare multidisciplinary and non-multidisciplinary clinics. METHODS: In this study, we compared the qualit...

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Autores principales: Carminatti, Moisés, Fernandes, Natália Maria Silva, Colugnati, Fernando Antonio Basile, Sanders-Pinheiro, Helady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428639/
https://www.ncbi.nlm.nih.gov/pubmed/33346316
http://dx.doi.org/10.1590/2175-8239-JBN-2019-0239
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author Carminatti, Moisés
Fernandes, Natália Maria Silva
Colugnati, Fernando Antonio Basile
Sanders-Pinheiro, Helady
author_facet Carminatti, Moisés
Fernandes, Natália Maria Silva
Colugnati, Fernando Antonio Basile
Sanders-Pinheiro, Helady
author_sort Carminatti, Moisés
collection PubMed
description INTRODUCTION: Multidisciplinary clinics are the best approach towards Chronic Kidney Disease (CKD) patients in pre-dialysis phases. The few studies regarding kidney transplant recipients (KTR) compare multidisciplinary and non-multidisciplinary clinics. METHODS: In this study, we compared the quality of multidisciplinary CKD care between 101 KTR and 101 propensity score-matched non-transplant pre-dialysis patients (PDP). Prevalence of patients without specific treatment at any time and percent time without specific treatment for CKD complications were the main outcomes and patient and kidney function survival, glomerular filtration rate (GFR) decline, prevalence of CKD-related complications, and percent time within therapeutic goals were the exploratory ones. RESULTS: Time within most goals was similar between the groups, except for diastolic blood pressure (83.4 vs. 77.3%, RR 0.92, CI 0.88-0.97, p = 0.002) and hypertriglyceridemia (67.7 vs. 58.2%, OR 0.85, CI 0.78-0.93, p < 0.001), better in non-transplant PDP, and for proteinuria (92.7 vs. 83.5%, RR 1.1, CI 1.05-1.16, p < 0.001), better in KTR. Patient survival and GFR decline were similar between the groups, although non-transplant PDP tended to progress earlier to dialysis (9.9% vs. 6.9%, HR 0.39, p = 0.07, CI 0.14-1.08). DISCUSSION: The similar findings between non-transplant PDP and KTR suggests that good and comparable quality of multidisciplinary is a valid strategy for promoting optimal clinical management of CKD-related complications in KTR.
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spelling pubmed-84286392021-09-16 Similar quality in chronic kidney disease multidisciplinary follow-up between kidney Carminatti, Moisés Fernandes, Natália Maria Silva Colugnati, Fernando Antonio Basile Sanders-Pinheiro, Helady J Bras Nefrol Original Article INTRODUCTION: Multidisciplinary clinics are the best approach towards Chronic Kidney Disease (CKD) patients in pre-dialysis phases. The few studies regarding kidney transplant recipients (KTR) compare multidisciplinary and non-multidisciplinary clinics. METHODS: In this study, we compared the quality of multidisciplinary CKD care between 101 KTR and 101 propensity score-matched non-transplant pre-dialysis patients (PDP). Prevalence of patients without specific treatment at any time and percent time without specific treatment for CKD complications were the main outcomes and patient and kidney function survival, glomerular filtration rate (GFR) decline, prevalence of CKD-related complications, and percent time within therapeutic goals were the exploratory ones. RESULTS: Time within most goals was similar between the groups, except for diastolic blood pressure (83.4 vs. 77.3%, RR 0.92, CI 0.88-0.97, p = 0.002) and hypertriglyceridemia (67.7 vs. 58.2%, OR 0.85, CI 0.78-0.93, p < 0.001), better in non-transplant PDP, and for proteinuria (92.7 vs. 83.5%, RR 1.1, CI 1.05-1.16, p < 0.001), better in KTR. Patient survival and GFR decline were similar between the groups, although non-transplant PDP tended to progress earlier to dialysis (9.9% vs. 6.9%, HR 0.39, p = 0.07, CI 0.14-1.08). DISCUSSION: The similar findings between non-transplant PDP and KTR suggests that good and comparable quality of multidisciplinary is a valid strategy for promoting optimal clinical management of CKD-related complications in KTR. Sociedade Brasileira de Nefrologia 2020-12-18 2021 /pmc/articles/PMC8428639/ /pubmed/33346316 http://dx.doi.org/10.1590/2175-8239-JBN-2019-0239 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Carminatti, Moisés
Fernandes, Natália Maria Silva
Colugnati, Fernando Antonio Basile
Sanders-Pinheiro, Helady
Similar quality in chronic kidney disease multidisciplinary follow-up between kidney
title Similar quality in chronic kidney disease multidisciplinary follow-up between kidney
title_full Similar quality in chronic kidney disease multidisciplinary follow-up between kidney
title_fullStr Similar quality in chronic kidney disease multidisciplinary follow-up between kidney
title_full_unstemmed Similar quality in chronic kidney disease multidisciplinary follow-up between kidney
title_short Similar quality in chronic kidney disease multidisciplinary follow-up between kidney
title_sort similar quality in chronic kidney disease multidisciplinary follow-up between kidney
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428639/
https://www.ncbi.nlm.nih.gov/pubmed/33346316
http://dx.doi.org/10.1590/2175-8239-JBN-2019-0239
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