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Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway

AIM: The aim of this study was to investigate the effect and underlying pathway of pyrroline-5-carboxylate reductase-2 (PYCR2) on colorectal cancer (CRC). METHODS: The Cancer Genome Atlas (TCGA) database was used to analyze PYCR2 expression levels and clinical information. Cell proliferation was eva...

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Detalles Bibliográficos
Autores principales: Yin, Feng, Huang, Xiaoxia, Xuan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429024/
https://www.ncbi.nlm.nih.gov/pubmed/34512817
http://dx.doi.org/10.1155/2021/9950663