Human cell transformation by combined lineage conversion and oncogene expression

Cancer is the most complex genetic disease known, with mutations implicated in more than 250 genes. However, it is still elusive which specific mutations found in human patients lead to tumorigenesis. Here we show that a combination of oncogenes that is characteristic of liver cancer (CTNNB1, TERT,...

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Detalles Bibliográficos
Autores principales: Sahu, Biswajyoti, Pihlajamaa, Päivi, Zhang, Kaiyang, Palin, Kimmo, Ahonen, Saija, Cervera, Alejandra, Ristimäki, Ari, Aaltonen, Lauri A., Hautaniemi, Sampsa, Taipale, Jussi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429043/
https://www.ncbi.nlm.nih.gov/pubmed/34302118
http://dx.doi.org/10.1038/s41388-021-01940-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429043/
https://www.ncbi.nlm.nih.gov/pubmed/34302118
http://dx.doi.org/10.1038/s41388-021-01940-0

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