Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas

A 74-year-old woman with a cyst in her pancreatic tail was referred to our hospital. Computed tomography confirmed a large cystic lesion with irregular wall thickening, abdominal lymph node swelling, and ascites. We diagnosed her with an unresectable mucinous cystic neoplasm, since ascites cytology...

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Autores principales: Miwa, Haruo, Sugimori, Kazuya, Ishii, Tomohiro, Funaoka, Akihiro, Tsuchiya, Hiromi, Suzuki, Yoshimasa, Sugimori, Makoto, Nishimura, Masaki, Tozuka, Yuichiro, Komiyama, Satoshi, Sato, Takeshi, Kaneko, Takashi, Numata, Kazushi, Maeda, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429298/
https://www.ncbi.nlm.nih.gov/pubmed/33642489
http://dx.doi.org/10.2169/internalmedicine.6755-20
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author Miwa, Haruo
Sugimori, Kazuya
Ishii, Tomohiro
Funaoka, Akihiro
Tsuchiya, Hiromi
Suzuki, Yoshimasa
Sugimori, Makoto
Nishimura, Masaki
Tozuka, Yuichiro
Komiyama, Satoshi
Sato, Takeshi
Kaneko, Takashi
Numata, Kazushi
Maeda, Shin
author_facet Miwa, Haruo
Sugimori, Kazuya
Ishii, Tomohiro
Funaoka, Akihiro
Tsuchiya, Hiromi
Suzuki, Yoshimasa
Sugimori, Makoto
Nishimura, Masaki
Tozuka, Yuichiro
Komiyama, Satoshi
Sato, Takeshi
Kaneko, Takashi
Numata, Kazushi
Maeda, Shin
author_sort Miwa, Haruo
collection PubMed
description A 74-year-old woman with a cyst in her pancreatic tail was referred to our hospital. Computed tomography confirmed a large cystic lesion with irregular wall thickening, abdominal lymph node swelling, and ascites. We diagnosed her with an unresectable mucinous cystic neoplasm, since ascites cytology revealed adenocarcinoma. The patient received chemotherapy up to the fifth line for 55.2 months. Gemcitabine plus nab-paclitaxel and modified FOLFIRINOX achieved a partial response with a progression-free survival time of 12.1 and 20.4 months, respectively. The overall survival time from the beginning of first-line chemotherapy was 69.4 months.
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spelling pubmed-84292982021-09-24 Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas Miwa, Haruo Sugimori, Kazuya Ishii, Tomohiro Funaoka, Akihiro Tsuchiya, Hiromi Suzuki, Yoshimasa Sugimori, Makoto Nishimura, Masaki Tozuka, Yuichiro Komiyama, Satoshi Sato, Takeshi Kaneko, Takashi Numata, Kazushi Maeda, Shin Intern Med Case Report A 74-year-old woman with a cyst in her pancreatic tail was referred to our hospital. Computed tomography confirmed a large cystic lesion with irregular wall thickening, abdominal lymph node swelling, and ascites. We diagnosed her with an unresectable mucinous cystic neoplasm, since ascites cytology revealed adenocarcinoma. The patient received chemotherapy up to the fifth line for 55.2 months. Gemcitabine plus nab-paclitaxel and modified FOLFIRINOX achieved a partial response with a progression-free survival time of 12.1 and 20.4 months, respectively. The overall survival time from the beginning of first-line chemotherapy was 69.4 months. The Japanese Society of Internal Medicine 2021-03-01 2021-08-15 /pmc/articles/PMC8429298/ /pubmed/33642489 http://dx.doi.org/10.2169/internalmedicine.6755-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Miwa, Haruo
Sugimori, Kazuya
Ishii, Tomohiro
Funaoka, Akihiro
Tsuchiya, Hiromi
Suzuki, Yoshimasa
Sugimori, Makoto
Nishimura, Masaki
Tozuka, Yuichiro
Komiyama, Satoshi
Sato, Takeshi
Kaneko, Takashi
Numata, Kazushi
Maeda, Shin
Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas
title Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas
title_full Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas
title_fullStr Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas
title_full_unstemmed Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas
title_short Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas
title_sort multiple-line chemotherapy for a patient with unresectable mucinous cystic neoplasm of the pancreas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429298/
https://www.ncbi.nlm.nih.gov/pubmed/33642489
http://dx.doi.org/10.2169/internalmedicine.6755-20
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