Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion

Probst bundles are selectively seen in patients with agenesis of the corpus callosum (CC) and are thought to be homologous to the CC. We herein report a 19-year-old woman with partial agenesis of the CC. She developed acute encephalopathy during Bordetella pertussis infection. Brain magnetic resonan...

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Autores principales: Ohashi, Eri, Hayakawa, Itaru, Abe, Yuichi, Tsutsumi, Yoshiyuki, Kubota, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429303/
https://www.ncbi.nlm.nih.gov/pubmed/33642486
http://dx.doi.org/10.2169/internalmedicine.6840-20
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author Ohashi, Eri
Hayakawa, Itaru
Abe, Yuichi
Tsutsumi, Yoshiyuki
Kubota, Masaya
author_facet Ohashi, Eri
Hayakawa, Itaru
Abe, Yuichi
Tsutsumi, Yoshiyuki
Kubota, Masaya
author_sort Ohashi, Eri
collection PubMed
description Probst bundles are selectively seen in patients with agenesis of the corpus callosum (CC) and are thought to be homologous to the CC. We herein report a 19-year-old woman with partial agenesis of the CC. She developed acute encephalopathy during Bordetella pertussis infection. Brain magnetic resonance imaging (MRI) showed restricted diffusion of bilateral Probst bundles. She was treated with anti-epileptics and azithromycin and recovered with no neurological sequelae. Follow-up MRI showed the resolution of the diffusion abnormality. The characteristics of diffusion-weighted images on brain MRI and clinical course mimicked those in cases of clinically mild encephalopathy/encephalitis with reversible splenial lesion.
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spelling pubmed-84293032021-09-24 Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion Ohashi, Eri Hayakawa, Itaru Abe, Yuichi Tsutsumi, Yoshiyuki Kubota, Masaya Intern Med Case Report Probst bundles are selectively seen in patients with agenesis of the corpus callosum (CC) and are thought to be homologous to the CC. We herein report a 19-year-old woman with partial agenesis of the CC. She developed acute encephalopathy during Bordetella pertussis infection. Brain magnetic resonance imaging (MRI) showed restricted diffusion of bilateral Probst bundles. She was treated with anti-epileptics and azithromycin and recovered with no neurological sequelae. Follow-up MRI showed the resolution of the diffusion abnormality. The characteristics of diffusion-weighted images on brain MRI and clinical course mimicked those in cases of clinically mild encephalopathy/encephalitis with reversible splenial lesion. The Japanese Society of Internal Medicine 2021-03-01 2021-08-15 /pmc/articles/PMC8429303/ /pubmed/33642486 http://dx.doi.org/10.2169/internalmedicine.6840-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ohashi, Eri
Hayakawa, Itaru
Abe, Yuichi
Tsutsumi, Yoshiyuki
Kubota, Masaya
Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion
title Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion
title_full Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion
title_fullStr Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion
title_full_unstemmed Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion
title_short Transient Probst Bundle Diffusion Restriction: An Acute Encephalopathy Equivalent to Clinically Mild Encephalopathy with a Reversible Splenial Lesion
title_sort transient probst bundle diffusion restriction: an acute encephalopathy equivalent to clinically mild encephalopathy with a reversible splenial lesion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429303/
https://www.ncbi.nlm.nih.gov/pubmed/33642486
http://dx.doi.org/10.2169/internalmedicine.6840-20
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