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Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis
Physical inactivity is discussed as one of the most detrimental influences for lifestyle-related medical complications such as obesity, heart disease, hypertension, diabetes and premature mortality in in- and outpatients with major depressive disorder (MDD). In contrast, intervention studies indicat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429392/ https://www.ncbi.nlm.nih.gov/pubmed/34282468 http://dx.doi.org/10.1007/s00406-021-01299-z |
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author | Görgülü, Esra Bieber, Miriam Engeroff, Tobias Zabel, Kirsten Etyemez, Semra Prvulovic, David Reif, Andreas Oertel, Viola |
author_facet | Görgülü, Esra Bieber, Miriam Engeroff, Tobias Zabel, Kirsten Etyemez, Semra Prvulovic, David Reif, Andreas Oertel, Viola |
author_sort | Görgülü, Esra |
collection | PubMed |
description | Physical inactivity is discussed as one of the most detrimental influences for lifestyle-related medical complications such as obesity, heart disease, hypertension, diabetes and premature mortality in in- and outpatients with major depressive disorder (MDD). In contrast, intervention studies indicate that moderate-to-vigorous-intensity physical activity (MVPA) might reduce complications and depression symptoms itself. Self-reported data on depression [Beck-Depression-Inventory-II (BDI-II)], general habitual well-being (FAHW), self-esteem and physical self-perception (FAHW, MSWS) were administrated in a cross-sectional study with 76 in- and outpatients with MDD. MVPA was documented using ActiGraph wGT3X + ® accelerometers and fitness was measured using cardiopulmonary exercise testing (CPET). Subgroups were built according to activity level (low PA defined as MVPA < 30 min/day, moderate PA defined as MVPA 30–45 min/day, high PA defined as MVPA > 45 min/day). Statistical analysis was performed using a Mann–Whitney U and Kruskal–Wallis test, Spearman correlation and mediation analysis. BDI-II scores and MVPA values of in- and outpatients were comparable, but fitness differed between the two groups. Analysis of the outpatient group showed a negative correlation between BDI-II and MVPA. No association of inpatient MVPA and psychopathology was found. General habitual well-being and self-esteem mediated the relationship between outpatient MVPA and BDI-II. The level of depression determined by the BDI-II score was significantly higher in the outpatient low- and moderate PA subgroups compared to outpatients with high PA. Fitness showed no association to depression symptoms or well-being. To ameliorate depressive symptoms of MDD outpatients, intervention strategies should promote habitual MVPA and exercise exceeding the duration recommended for general health (≥ 30 min/day). Further studies need to investigate sufficient MVPA strategies to impact MDD symptoms in inpatient settings. Exercise effects seem to be driven by changes of well-being rather than increased physical fitness. |
format | Online Article Text |
id | pubmed-8429392 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-84293922021-09-24 Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis Görgülü, Esra Bieber, Miriam Engeroff, Tobias Zabel, Kirsten Etyemez, Semra Prvulovic, David Reif, Andreas Oertel, Viola Eur Arch Psychiatry Clin Neurosci Original Paper Physical inactivity is discussed as one of the most detrimental influences for lifestyle-related medical complications such as obesity, heart disease, hypertension, diabetes and premature mortality in in- and outpatients with major depressive disorder (MDD). In contrast, intervention studies indicate that moderate-to-vigorous-intensity physical activity (MVPA) might reduce complications and depression symptoms itself. Self-reported data on depression [Beck-Depression-Inventory-II (BDI-II)], general habitual well-being (FAHW), self-esteem and physical self-perception (FAHW, MSWS) were administrated in a cross-sectional study with 76 in- and outpatients with MDD. MVPA was documented using ActiGraph wGT3X + ® accelerometers and fitness was measured using cardiopulmonary exercise testing (CPET). Subgroups were built according to activity level (low PA defined as MVPA < 30 min/day, moderate PA defined as MVPA 30–45 min/day, high PA defined as MVPA > 45 min/day). Statistical analysis was performed using a Mann–Whitney U and Kruskal–Wallis test, Spearman correlation and mediation analysis. BDI-II scores and MVPA values of in- and outpatients were comparable, but fitness differed between the two groups. Analysis of the outpatient group showed a negative correlation between BDI-II and MVPA. No association of inpatient MVPA and psychopathology was found. General habitual well-being and self-esteem mediated the relationship between outpatient MVPA and BDI-II. The level of depression determined by the BDI-II score was significantly higher in the outpatient low- and moderate PA subgroups compared to outpatients with high PA. Fitness showed no association to depression symptoms or well-being. To ameliorate depressive symptoms of MDD outpatients, intervention strategies should promote habitual MVPA and exercise exceeding the duration recommended for general health (≥ 30 min/day). Further studies need to investigate sufficient MVPA strategies to impact MDD symptoms in inpatient settings. Exercise effects seem to be driven by changes of well-being rather than increased physical fitness. Springer Berlin Heidelberg 2021-07-19 2021 /pmc/articles/PMC8429392/ /pubmed/34282468 http://dx.doi.org/10.1007/s00406-021-01299-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Görgülü, Esra Bieber, Miriam Engeroff, Tobias Zabel, Kirsten Etyemez, Semra Prvulovic, David Reif, Andreas Oertel, Viola Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
title | Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
title_full | Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
title_fullStr | Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
title_full_unstemmed | Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
title_short | Physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
title_sort | physical activity, physical self-perception and depression symptoms in patients with major depressive disorder: a mediation analysis |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429392/ https://www.ncbi.nlm.nih.gov/pubmed/34282468 http://dx.doi.org/10.1007/s00406-021-01299-z |
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