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SLC4A2 anion exchanger promotes tumour cell malignancy via enhancing net acid efflux across golgi membranes

Proper functioning of each secretory and endocytic compartment relies on its unique pH micro-environment that is known to be dictated by the rates of V-ATPase-mediated H(+) pumping and its leakage back to the cytoplasm via an elusive “H(+) leak” pathway. Here, we show that this proton leak across Go...

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Detalles Bibliográficos
Autores principales: Khosrowabadi, Elham, Rivinoja, Antti, Risteli, Maija, Tuomisto, Anne, Salo, Tuula, Mäkinen, Markus J., Kellokumpu, Sakari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429400/
https://www.ncbi.nlm.nih.gov/pubmed/34279699
http://dx.doi.org/10.1007/s00018-021-03890-y

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