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Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling

Pseudomonas aeruginosa is an opportunistic pathogen capable of stably adapting to the antiseptic octenidine by an unknown mechanism. Here we characterise this adaptation, both in the laboratory and a simulated clinical setting, and identify a novel antiseptic resistance mechanism. In both settings,...

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Detalles Bibliográficos
Autores principales: Bock, Lucy J., Ferguson, Philip M., Clarke, Maria, Pumpitakkul, Vichayanee, Wand, Matthew E., Fady, Paul-Enguerrand, Allison, Leanne, Fleck, Roland A., Shepherd, Matthew J., Mason, A. James, Sutton, J. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429429/
https://www.ncbi.nlm.nih.gov/pubmed/34504285
http://dx.doi.org/10.1038/s42003-021-02566-4