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Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling
Pseudomonas aeruginosa is an opportunistic pathogen capable of stably adapting to the antiseptic octenidine by an unknown mechanism. Here we characterise this adaptation, both in the laboratory and a simulated clinical setting, and identify a novel antiseptic resistance mechanism. In both settings,...
Autores principales: | Bock, Lucy J., Ferguson, Philip M., Clarke, Maria, Pumpitakkul, Vichayanee, Wand, Matthew E., Fady, Paul-Enguerrand, Allison, Leanne, Fleck, Roland A., Shepherd, Matthew J., Mason, A. James, Sutton, J. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8429429/ https://www.ncbi.nlm.nih.gov/pubmed/34504285 http://dx.doi.org/10.1038/s42003-021-02566-4 |
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